We evaluated microfocal X-ray-computed tomography (micro-CT) as a method to visualize lung architecture two and three dimensionally and to obtain morphometric data. Inflated porcine lungs were fixed by formaldehyde ventilation. Tissue samples (8-mm diameter, 10-mm height) were stained with osmium tetroxide, and 400 projection images (1,024 x 1,024 pixel) were obtained. Continuous isometric micr...

We investigated whether a relationship exists between frontal lobe volume and fluid intelligence as measured by both Cattell's Culture Fair test and the Wechsler Adult Intelligence Scale-Revised (WAIS-R) Performance scale, but not with crystallized intelligence as measured by the WAIS-R Verbal scale, in healthy adults, using two well-established image analysis techniques applied to high-resolut...

amiodarone is used in treatment of cardiac arrhythmias. therapeutic use of amiodarone is limited by its side effects, including pulmonary toxicity. human placenta extract (hpe) contains a variety of bio-active substances. thus, the present study aimed to quantitatively evaluate the protective effects of hpe on the structural lung changes induced by amiodarone using stereological methods. spragu...

objective: to determine the effects of topical administration of 20% oltipraz solution on histomorphometrical and stereological aspects of skin tissue in full thickness skin wounds in laboratory rats. methods: thirty-six male wistar portion rats (220±20 g) were randomly divided into three groups (n=12). on the first day of experimentation, a 1-cm 2 circular wound was made on the posterior surfa...

BACKGROUND Cardiac fibrosis disrupts the normal myocardial structure and has a direct impact on heart function and survival. Despite already available digital methods, the pathologist's visual score is still widely considered as ground truth and used as a primary method in histomorphometric evaluations. The aim of this study was to compare the accuracy of digital image analysis tools and the pa...

Thermo-deformable plastic films experience an optical birefringence phenomenon when they are subjected to mechanical strain, this phenomenon can be described by color fringes behavior observed in sequences of images acquired through photoelasticity assemblies. This paper proposes a temporary morphological analysis that color fringes experience when the plastic film is deformed. For the image an...