This past October, I published an editorial (Blatt, 2015) appraising the social media phenomenon of PubPeer. I raised several issues with the Web site that I maintain do not serve the scientific community and will only entrench many of the underlying attitudes and behaviors that PubPeer claims it seeks to counter. The response tomyeditorial exceededall expectations— in 18 days it garnered 348 c...

This microspectrophotometric (MSP) study has confirmed that goldfish, acclimated under a certain light and temperature regimen, possess mixtures of porphyropsin and rhodopsin in their rod outer segments. Moreover, the MSP spectra from the red, green and blue cones of these acclimated goldfish also shifted to shorter wavelengths from spectra of pure 3-dehydroretinal based visual pigments. Thus, ...

increasingly valuable, as they allow rapid generation of transgenic animals or targeted knockdowns and investigation of the systemic changes that result from targeted manipulation of neuronal activity (Kasuya et al., 2009; Tessier and Broadie, 2009; White and Peabody, 2009; Hirata et al., 2010). Molecular systems for monitoring ion flux across the neuronal plasma membrane as well as high-throug...

We study the glassy transition for simple liquids in the hypernetted chain (HNC) approximation by means of an effective potential recently introduced. Integrating the HNC equations for hard spheres, we find a transition scenario analogous to that of the long-range disordered systems with ‘one-step replica symmetry breaking’. Our results agree qualitatively with Monte Carlo simulations of three-...

In 2003, C. Zandonella reviewed in Nature how much was achieved of the 1999 promise to grow a functioning heart in the dish in a decade and what the perspectives were at that time.1 Today, more than a decade after its public prediction, the heart in the dish is still an unfulfilled dream, but repairing injured hearts with engineered myocardial tissue patches is a viable and increasingly realist...

– The effect of polydispersity on the phase behaviour of hard spheres is examined using a moment projection method. It is found that the Boublik-Mansoori-Carnahan-StarlingLeland equation of state shows a spinodal instability for a bimodal distribution if the large spheres are sufficiently polydisperse, and if there is sufficient disparity in mean size between the small and large spheres. The sp...

GABAA receptors are predominantly composed of and isoforms in the brain. It has been proposed that receptors mediate phasic inhibition, whereas receptors mediate tonic inhibition. Propofol (2,6-di-isopropylphenol), a widely used anesthetic drug, exerts its effect primarily by modulating GABAA receptors; however, the effects of propofol on the kinetic properties of and receptors are uncertain. W...

Several groups have characterized the pharmacology of 4or 6 3 -containing GABAA receptors expressed in different cell systems. We have previously demonstrated that the pharmacological profiles of a series of GABAA receptor agonists are highly dependent on the subunit and little on the and subunits, so to further understand the contribution of the different subunits in the GABAA receptor complex...

To understand the full significance of computer music's instrumentality, I propose to extend Heidegger's reflection on technology to a broader complex of concepts that Michel Foucault defined. This reflection leads to a perspective that highlights issues of somaticity and performative textuality in computer music. It also helps underscore a new understanding of subjectivity, a new way of being-...

Few topics in Arendt's corpus have garnered more attention than her analysis of the dangers inherent Adolf Eichmann's inability to think. Eichmann revealed what Arendt describes as banality evil, a new kind evil born not monstrous or demonic motives but thoughtlessness (Arendt, 2006, p. 54).11 Hereafter EJ. Yet, while made clear urgent need we think, scholars remain at odds whether succeeds dem...