Lysolecithin exhibited bactericidal effect on mycobacteria and staphylococci, but not on E. coli. The effect on staphylococci was manifested shortly after exposure, but that on mycobacteria was of the delayed type. The mycobactericidal activity was dependent on the fatty acid moiety of the chemical structure reflecting the cytotoxicity of the free form. The activity on staphylococci was not, ho...

background and objective: reliable methods of detection of antimicrobial resistance are of paramount importance in the treatment and management of infections caused by coagulase negative staphylococci (cons). the objective of the present study was to compare and evaluate the performance of disc diffusion and e test (epsilometer test) methods for antimicrobial testing of coagulase negative staph...

A total of 842 staphylococci isolated from clinical material over an eight-month period and regarded as probable pathogens were identified according to lyogroup. Almost half the isolates belonged to lyogroups other than lyogroup I (Staphylococcus aureus), suggesting that coagulase-negative staphylococci are increasingly involved in human infections. All isolates were tested for sensitivity to 1...

A new scheme for identification of coagulase-negative staphylococci was applied to 138 consecutive urinary isolates of coagulase-negative staphylococci. The most common species were Staphylococcus epidermidis (53%), S. hominis (12%), and S. haemolyticus (10%). S. saprophyticus comprised only 5%. The disk method for antibiotic susceptibility for all species grouped together disclosed resistance ...

The CLSI M100-S19 document has recommended the disuse of vancomycin disks for staphylococci and informed that studies on the action of teicoplanin in disk-diffusion testing should be performed. We describe the comparison of two methods, disk diffusion and broth microdilution, for determining teicoplanin susceptibility in clinical isolates of staphylococci. Overall results showed an aggregation ...

Two serogroups (B and E) of Pasteurella multocida associated with hemorrhagic septicemia in cattle were differentiated by a coagglutination test with antibody-coated staphylococci. The group antigen was soluble and heat stable. It was not detectable in unencapsulated cells or their heated extracts. Adsorbed onto human type O erythrocytes, it could be demonstrated by an indirect hemagglutination...

Of 150 coagulase-positive staphylococcal isolates from infections in dogs, 9 isolates with biochemical properties of human biotype were characteristically agglutinated by absorbed antiserum to staphylococcal strain 17, while only 110 of 141 isolates with biochemical properties of staphylococci of canine origin were agglutinated by absorbed antiserum to strain 61218. However, upon development of...

Coagulase-negative staphylococci are the most frequently isolated microorganisms in early prosthetic valve endocarditis. However, they rarely cause endocarditis in native valves. The profile of patients with left-sided native valve endocarditis by coagulase-negative staphylococci is unknown, because available data are scarce and outdated. We analyzed the epidemiological, clinical, radiographic,...

The comparative in vitro activity of RU 64004 (also known as HMR 3004), a new ketolide antibiotic, was tested by agar dilution against approximately 500 gram-positive organisms, including multiply resistant enterococci, streptococci, and staphylococci. All streptococci were inhibited by < or = 1 microg of RU 64004 per ml. The ketolide was more potent than other macrolides against erythromycin A...

Taxo A bacitracin disks (BBL Microbiology Systems, Cockeysville, Md.) were evaluated as a test for differentiating staphylococci from micrococci in clinical laboratories. All staphylococci tested were resistant to the disks, with no zone of growth inhibition. Zones of growth inhibition ranging from 10.5 to 25.0 mm in diameter were observed with all micrococci except two isolates which failed to...