In the nuclear genome of Saccharomyces cerevisiae, simple, repetitive DNA sequences (microsatellites) mutate at rates much higher than nonrepetitive sequences. Most of these mutations are deletions or additions of repeat units. The yeast mitochondrial genome also contains many microsatellites. To examine the stability of these sequences, we constructed a reporter gene (arg8(m)) containing out-o...

Individuals’ achievement goals are known to influence learning behaviors and academic achievement. However, prior research also indicates that undergraduates’ achievement goals for psychology coursework vary from assignment to assignment. The effect of stability of achievement goals on learning behaviors and outcomes has yet to be explored. This study examined how adolescents’ achievement goals...

nowadays because of various factors, including inappropriate land use, and indiscriminate exploitation of water resources, soil and vegetation, wide areas of the country were exposed to destruction of lands and desertification. therefore dealing with this situation requires a comprehensive land use program (water and land) and appropriate environment potency. the study area is patom district of...

Interleukin 2 (IL-2) therapies have antitumor activities against several neoplasms. In vitro these activities are enhanced by beta-interferon (IFN-beta). Therefore, we initiated a Phase I trial with a combination of IL-2 and IFN-beta three times weekly. The IFN-beta was administered i.v. Initially, the IL-2 was administered s.c. However, neutralizing antibody to the IL-2 developed in five patie...

conclusions kmc before and during heel lancing is a natural, easy to use, and cost-effective method to decrease pain in premature neonates. it is consistent with modern strategy of family-centered care in neonatal units. results the mean score of pain intensity during the intervention was significantly lower in the kmc position (p < 0/000). mean score of pain intensity at two minutes after inte...

This paper evaluates the impacts of new housing developments funded with the Low Income Housing Tax Credit (LIHTC), the largest federal project based housing program in the U.S., on the neighborhoods in which they are built. A discontinuity in the formula determining the magnitude of tax credits as a function of neighborhood characteristics generates pseudo-random assignment in the number of lo...

This is a quantitative exploratory, descriptive study performed with the objective to identify and analyze the performance of the average time of nursing care delivered to patients of the Inpatient Units of the University Hospital at University of São Paulo (UH-USP), from 2001 to 2005. The average nursing care time delivered to patients of the referred units was identified by applying of a math...

The recording capability of a microelectrode array in the cat dorsal root ganglion (DRG) was studied in 11 acute experiments, 373 single, discriminable sensory units were recorded on 587 electrodes (0.64 units/electrode). Sensory action potentials as large as 1750 microV were obtained (mean=132 microV). These were comparable to literature reports of the best DRG extracellular recordings made wi...

The recruitment order of motor units was studied with an electromyographic technique for secure identification of single motor unit potentials. It has been shown in previous studies of normal subjects that the recruitment order in sustained voluntary contraction is predominantly stable, and that motor units which increase slowly in discharge rate with increasing contraction strength and which a...