PURPOSE To detect mRNAs for somatostatin (somatotropin release-inhibiting factor [SRIF]) receptor subtypes 1 to 5 (sst(1) through sst(5)) in rabbit retinas by reverse transcription-polymerase chain reaction (RT-PCR) and to investigate the distribution of sst(1) by single- and double-label immunocytochemistry. METHODS Semiquantitative RT-PCR using sst-specific primers from mouse sequences was ...

[1] A molecular organic geochemical proxy (TEX86) for sea surface temperature (SST) is compared with a foraminifera‐based SST proxy (Mg/Ca) in a decadal‐resolution marine sedimentary record spanning the last 1000 years from the Gulf of Mexico. We assess the relative strengths of the organic and inorganic paleoceanographic techniques for reconstructing high‐resolution SST variability during rece...

Somatostatin (SST) is a gut peptide that is able to inhibit the growth of tumor cells in gastric cancer and other types of cancer. The present study investigated the mRNA and protein levels of SST and SST receptors (SSTRs) in human gastric cancer, and detected the DNA methylation of the SST promoter. The protein levels of SST were detected using a radioimmunoassay in 102 human gastric tissue sp...

BACKGROUND Somatostatin (SS)-binding sites have been demonstrated in human lymphoid tissues and peripheral blood cells. However, not much is known with respect to the SS receptor subtype (sst) expression pattern and the expression of SS itself in the immune system. OBJECTIVE The aim of this study was to evaluate the mRNA expression of the five known sst (sst(1-5)) in peripheral blood mononucl...

IDEAL STABILITY STUDIES FOR THREE AND FOUR PERIOD FLEXIBLE HELIACS. The stability properties of two realizations of the flexible Heliac concept presently under construction HI in Australia and TJ-ll in Spain are described. HI and TJ-ll equilibria, calculated by using the VMEC code, are analysed for their stability with respect to Mercier modes and, in the TJ-ll case, to low-n modes. In the heli...

The validation of sea surface temperature (SST) retrieved from the new sensor Visible Infrared Imaging Radiometer Suite (VIIRS) onboard the Suomi National Polar-Orbiting Partnership (S-NPP) Satellite is essential for the interpretation, use, and improvement of the new generation SST product. In this study, the magnitude and characteristics of uncertainties in S-NPP VIIRS SST produced by the Nav...

Targeting of G-protein coupled receptors (GPCRs) like somatostatin-14 (SST-14) could have a potential interest in delivery of anti-cancer agents to tumor cells. Attachment of SST to different nano-carriers e.g. polymeric nanoparticles is limited due to the difficulty of interaction between SST itself and those nano-carriers. Furthermore, the instability problems associated with the final formul...

We study the real-time dynamics retrieval from a time series via the time-frequency (TF) analysis with the minimal latency guarantee. While different from the well-known intrinsic latency definition in the filter design, a rigorous definition of intrinsic latency for different time-frequency representations (TFR) is provided, including the short time Fourier transform (STFT), synchrosqeezing tr...

OBJECTIVE Somatostatin (SST) is secreted by islet delta-cells and by extraislet neuroendocrine cells. SST receptors have been identified on alpha- and beta-cells, and exogenous SST inhibits insulin and glucagon secretion, consistent with a role for SST in regulating alpha- and beta-cell function. However, the specific intraislet function of delta-cell SST remains uncertain. We have used Sst(-/-...