BACKGROUND The Stockholm III Trial randomized patients with primary operable rectal cancers to either short-course radiotherapy (RT) with immediate surgery (SRT), short-course RT with surgery delayed 4-8 weeks (SRT-delay) or long-course RT with surgery delayed 4-8 weeks. This preplanned interim analysis examined the pathological outcome of delaying surgery. METHODS Patients randomized to the ...

INTRODUCTION The aim of this study was to investigate the feasibility of using two computer-administered neuropsychological tasks in a clinical trial involving participants with Parkinson's disease without dementia. The tasks, probabilistic reversal learning (PRL) and serial reaction time (SRT), target dorsolateral prefrontal cortex (SRT) and ventral striatal-orbitofrontal (PRL) functioning res...

OBJECTIVE The objective was to describe the speech intelligibility in noise test results among Dutch teenagers and young adults aged 12-24 years, using a national online speech reception threshold (SRT) test, the Earcheck. A secondary objective was to assess the effect of age and gender on speech intelligibility in noise. DESIGN Cross-sectional SRT data were collected over a 5-year period (20...

The clinical significance of sentence repetition tasks (SRTs) for assessing children's language ability is well-recognized. SRT has been identified as a good clinical marker for children with (specific) language impairment as it shows high diagnostic accuracy levels. Furthermore, qualitative analysis of repetition samples can provide information to be used for intervention protocols. Despite th...

Purpose Stereotactic radiation therapy (SRT) enables focused, short course, high dose per fraction radiation delivery to brain tumors that are less ideal for single fraction treatment because of size, shape, or close proximity to sensitive structures. We sought to identify optimal SRT treatment regimens for maximizing local control while minimizing morbidity. Methods and materials We performe...

The aim was to evaluate the clinical outcome of hypofractionated stereotactic radiotherapy (SRT) with CyberKnife for nonfunctioning pituitary adenoma. From October 2000 to March 2009, 100 patients with nonfunctioning pituitary adenoma were treated with hypofractionated SRT. Forty-three patients were male, and 57 were female. The patient's ages ranged from 16 to 82 years (median, 59 years). Five...

Introduction: Nasopharyngeal carcinoma (NPC) is commonly known as a radiosensitive tumor with the initial good response to radiation. Despite the improved outcome in loco regional control by the introduction of combining treatment, modern radiotherapy techniques and enhanced imaging studies, local recurrent after primary treatment with rate ranges from 15-58% in 5 years, stil...

This paper describes the design of a very high speed optoelectronic analog digital converter based on a digital division algorithm called SRT division using n–i(MQW)–n Self Electro-Optic Effect Device (SEED) technology. The proposed structure is a pipeline ADC. The SRT algorithm was chosen because it provides a redundancy at each stage of the pipeline. The amount of redundancy is dependent on t...

We have suggested that the Remote Distractor Effect (RDE), the elevation of average saccadic reaction time (SRT) induced by a task-irrelevant distractor, is a statistical consequence of a characteristic reshaping of the SRT distribution known as Saccadic Inhibition (SI) (Buoncore & McIntosh, 2008). In a recent paper, Walker and Benson (2013) argue against this idea, and claim that the RDE and S...

We have suggested that the Remote Distractor Effect (RDE), the elevation of average saccadic reaction time (SRT) induced by a task-irrelevant distractor, is a statistical consequence of a characteristic reshaping of the SRT distribution known as Saccadic Inhibition (SI) (Buoncore & McIntosh, 2008). In a recent paper, Walker and Benson (2013) argue against this idea, and claim that the RDE and S...