Recently, there has been great interest in developing finely pixellated position-sensitive scintillation detectors for ultra-high-resolution Positron Emission Tomography (PET) systems designed for breast cancer detection, diagnosis, and staging and for imaging small laboratory animals. We are developing a different high-resolution PET detector design that promotes nearly complete scintillation ...

Periodontal regeneration is an important part of regenerative medicine, with great clinical significance; however, the effects of nanotopography on the functions of periodontal ligament (PDL) stem cells (PDLSCs) and on PDLSC sheet based periodontal regeneration have never been explored. Titania nanotubes (NTs) layered on titanium (Ti) provide a good platform to study this. In the current study,...

Laser bending is an advanced process in sheet metal forming in which a laser heat source is used to shape the metal sheet. In this paper, temperature distribution in a mild steel sheet metal is investigated numerically and experimentally. Laser heat source is applied through curved paths in square sheet metal parts. Finite element (FE) simulation is performed with the ABAQUS/CAE standard softwa...

BACKGROUND There is an essential demand for tissue engineered autologous small-diameter vascular graft, which can function in arterial high pressure and flow circulation. We investigated the potential to engineer a three-layered robust and elastic artery using a novel hemodynamically-equivalent pulsatile bioreactor. METHODS AND RESULTS Endothelial cells (ECs), smooth muscle cells (SMCs), and ...

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Herein, a micro-patterned cell adhesive surface is prepared for the future design of medical devices. One-dimensional polydimethylsiloxane (PDMS) micro patterns were prepared by a photolithography process. We investigated the effect of microscale topographical patterned surfaces on decreasing the collective cell migration rate. PDMS substrates were prepared through soft lithography using Si mol...

Endoblast and hypoblast tissue, dissected from early chick embryos, was explanted and cultured on glass or plastic substrata. These tissues grew rapidly to form epithelial sheets. Under the same conditions, mesoderm, dissected without the aid of dissociating agents, grew poorly. After 24 h in culture, the mesoderm explants consisted of a sparse outgrowth of fibroblast-like cells. When pieces of...

This paper develops a fully microfounded two-sector DGE model for a small open economy subject to credit market imperfections (CMIs) and balance sheet problems (due to the presence of a currency mismatch). Specifically, some agents in this economy face credit constraints to finance investment due to information asymmetries and, while their assets are denominated in the domestic currency, their ...

A special instrument has been built to measure the coercivity directly on steel sheets without having to cut samples. It will be used to perform the 8000 coercivity measurements which will be needed during the production of the ll'OOO ton of steel sheets for the LEP dipole magnets. The coercimeter allows local and directional coercivity measurements to be made on a steel sheet with an accuracy ...

A simple If-dimensional continental ice sheet model is presented. The model is based on Nye’s (1959) proposal to express the vertical mean horizontal ice-velocity as u = BC, where r, is the basal shear stress and B and m are constants. Essentially, the spread of ice is governed by a nonlinear diffusion equation for the ice thickness. The diffusivity increases with both ice thickness and surface...