Purpose The aim of the study is to characterise safety signals based on Dutch spontaneous reporting system (SRS) and investigate association between signal characteristics Product Information (PI) update stratified by approval type: centrally authorised products (CAPs) versus nationally decentralised (NAPs). Methods This evaluates full cohort disseminated from SRS in period 2008 2017. Each retr...

The data obtained from case-control sampling may suffer from selection or reporting bias, resulting in biased estimation of the parameter(s) of interest by standard analysis of case-control data. In this work, the problem of reporting bias is dealt with by introducing the concept of reporting probability. Then, considering a reference sample from the source population, we obtain unbiased estima...

Background: Spontaneous reporting of adverse drug reaction is globally practiced it under pharmacovigilance programme. But the major drawback of this system is underreporting. In this context the present survey was conducted, to assess the knowledge, attitude and practice of spontaneous ADR reporting among doctors and nurses in a tertiary care teaching hospital in South India. Methods: A cross-...

background about one third of unwanted reported medication consequences are due to medication errors, resulting in one-fifth of hospital injuries. objectives the aim of this study was determined formal and informal medication errors of nurses and the level of importance of factors in refusal to report medication errors among nurses. patients and methods the cross-sectional study was done on the...

BACKGROUND Miscarriages are a common pregnancy complication affecting about 10-15% of pregnancies. Miscarriages may be associated with a myriad of psychiatric morbidity at various timelines after the event. Depression has been shown to affect about 10-20% of all women following a miscarriage. However, no data exists in the local setting informing on the prevalence of post-miscarriage depression...