A case of spontaneous intracranial hypotension syndrome is described. Computed tomography showed slit ventricles with tight basal cisterns. Prompt improvement of symptoms was achieved by intramuscular dexamethasone treatment. A follow-up CT scan demonstrated re-expansion of ventricles and basal cisterns.

Received 2/28/2004; revised 4/1/2004; accepted 4/5/2004. For correspondence or reprints contact: Ruoh-Fang Yen, M.D., Department of Nuclear Medicine, National Taiwan University Hospital, 7 Chung-Shan South Road, Taipei 100, Taiwan. Tel: (886)2-23562480, Fax: (886)2-23957855, E-mail: [email protected] It has been postulated that spontaneous intracranial hypotension is caused by the rupture ...

Autoimmune thyroid disorders such as hyperthyroidism and hypothyroidism are rare causes of intracranial pressure alterations. We present a case of spontaneous intracranial hypotension associated with Graves’ disease which was not reported previously in the literature. A 42-year-old woman was admitted to our institution because of a sudden developed headache, neck pain, nausea and vomiting. The ...

This case expands our knowledge of the spectrum of manifestations of spontaneous intracranial hypotension. A 42-year-old man was seen for a third neurolog-ical opinion for obtundation. He presented with a 1-month history of new-onset, daily, intense, right-sided headaches (information about postural precipitation is not available). A magnetic resonance imaging (MRI) scan of the brain showed dif...

Intracranial hypotension is not an uncommon diagnosis after lumbar puncture or neurosurgery. However, spontaneous intracranial hypotension (SIH) is a poorly understood entity that can present with a wide variety of symptoms/signs ranging from headache to coma. SIH may result from an occult spinal cerebrospinal fluid (CSF) leak. Alternatively, because a CSF leak is not always found, some posit t...

In Response To: Salazar R. Spontaneous intracranial hypotension associated with kinetic tremor and ataxia. Tremor Other Hyperkinet Mov. 2016; 6. doi: 10.7916/D8HQ3ZN5.

Spontaneous intracranial hypotension, of which brain slump is an extreme expression, is caused by a cerebrospinal fluid leak. The reason the leak develops in the first place, however, is unknown, and some cases can be very difficult to manage. We describe a patient with severe symptoms of spontaneous intracranial hypotension and brain slump documented by magnetic resonance imaging whose clinica...

A literature search found no clinical trials or guidelines addressing the management of spontaneous intracranial hypotension (SIH). Based on the available literature and expert opinion, we have developed recommendations for the diagnosis and management of SIH. For typical cases, we recommend brain magnetic resonance (MR) imaging with gadolinium to confirm the diagnosis, and conservative measure...

We report three patients with spontaneous intracranial hypotension in whom spinal MR imaging revealed ventral extradural fluid collections that were centered at the cervicothoracic junction in two patients and extended throughout the entire spine in the third patient. These spinal fluid collections most likely resulted from the accumulation of CSF at the site of dural leakage. Knowledge of this...

A 44-year-old woman presented with sudden onset of occipital headache and neck stiffness for 3 weeks. The headache was pulling in character and worse in the morning (visual analogue scale pain score of 8). Coughing, straining when passing a stool, and postural change (either going from a lying to an erect position or vice versa) provoked the headache. It was associated with vertigo, nausea, and...