Objective(s): Prostate cancer is the world’s leading cause of cancer and the second cause of cancer-related death in men after lung cancer. Differentiation of prostate adenocarcinoma from benign prostate lesions and hyperplasia sometimes cannot be done on the basis of morphologic findings. Considering the fact that in the prostate adenocarcinoma there is no basal cell layer, basal cell markers ...

Introduction: Colon adenocarcinoma is one of the foremost causes of cancer mortality. Oral metastasis of colon adenocarcinoma is, however, rare and indicates an end-stage disease process.   Case Report: We report a case of a 69-year-old female with a gingival mass diagnosed with colon adenocarcinoma and liver metastasis after one year. A swelli...

objective: to evaluate the potentiality of ovcar–3 cell line of ovarian adenocarcinoma as a xenograft model for ovarian adenocarcinoma in nude mice. materials and methods: the cell line isolated from advanced human ovarian adenocarcinoma, were inoculated to eight nude mice and two months later. established tumors were transferred to pathology laboratory to be prepared by h&e; staining and immun...

UNLABELLED A case of spontaneous regression of colon cancer is reported. The patient, an 80-year-old man, was referred to hospital in January 2004. Colonoscopy revealed a type 2 tumour in the transverse colon which was diagnosed as an adenocarcinoma. A computed tomography scan also revealed a right renal tumour. Urological examination disclosed renal cell cancer. The patient subsequently refuse...

Tumor lysis syndrome (TLS) is an oncological emergency caused by massive cytolysis of malignant cells. This syndrome eventually induces metabolic abnormalities. TLS is observed mainly among tumors with rapid cell proliferation or high sensitivity to antineoplastic treatment. In rare cases, TLS occurs without any cytotoxic treatment. Previous reports have shown that alternative stress including ...

We show correlation between strong and decreased NY-ESO-1specific immunity with spontaneous regression and subsequent recurrence, respectively, in a long-surviving patient with an NY-ESO-1-expressing lung adenocarcinoma. An integrated immune response consisting of IgG antibody, as well as CD4 and CD8 T cells, against NY-ESO-1 was observed at the time of spontaneous regression of multiple pleura...

It has been observed that transplanted tumors in rats and mice sometimes regress during preg nancy (3, 6), the tumor growth usually being more noticeably inhibited in the later stages of preg nancy (1). Spontaneous breast adenocarcinoma in FI hybrids (from C57BL females mated to RIII males) have been reported to regress after par turition or "a little before" parturition (4). This report summar...

A 42-year-old female patient was admitted for recurrent bilateral spontaneous pneumothorax. High resolution computed tomography showed bilateral pneumothorax and numerous round and oval, thin-walled lung cysts. Microscopically, each small cyst was composed of distended subpleural alveolar spaces. Tumor cells, characteristic of acinar adenocarcinoma, obstructed and narrowed the terminal bronchio...

The immunosurveillance of transformed cells by the immune system remains one of the most controversial and poorly understood areas of immunity. Gene-targeted mice have greatly aided our understanding of the key effector molecules in tumor immunity. Herein, we describe spontaneous tumor development in gene-targeted mice lacking interferon (IFN)-gamma and/or perforin (pfp), or the immunoregulator...

background: neuroectodermal tumors (pnet) are malignant small cells neoplasm mainly occurring in children but can occur at any age. extensive bleeding into the pleural cavity is rare in children. hemothorax would be compatible with a variety of congenital anomalies including sequestration, patent ductus artreiosus, and pulmonary arteriovenous malformation. case report: a 2.5-years old girl who ...