نتایج جستجو برای: spiro heterobicyclic rings
تعداد نتایج: 50633 فیلتر نتایج به سال:
Heterocyclic compounds containing β-lactum structure with different hetero atoms are found to show biological activities1. In the present work, it has been synthesized the semicarbozone and thiosemicarbozone derivatives of 3-methyl-2,6-diphenylpiperidin-4-one followed bycyclisation to get the spiro compounds. These spiro compounds. The spiro products have been characterized by C,H,M analysis, I...
The asymmetric unit of the title compound, C26H25ClN2O3, contains two independent mol-ecules (A and B). The conformation of the two mol-ecules differs essentially in the dihedral angle involving the two benzene rings. They are inclined to one another by 52.47 (10) in A and by 31.75 (11)° in B. In both mol-ecules, the six-membered piperidin-3-one rings have chair conformations. In mol-ecule A, a...
The asymmetric unit of the title compound, C29H24FNO5·0.5CH3OH, contains two independent mol-ecules and a one methanol solvent mol-ecule. The methanol mol-ecule is O-H⋯O hydrogen bonded to one of the independent mol-ecules. The pyrrolidine rings in both mol-ecules adopt half-chair conformations, while the cyclo-pentane rings within the indane groups are in flattened envelope conformations, with...
the development of multicomponent reactions (mcrs) designed to produce elaborate biologically active compounds has become an important area of research in organic, combinatorial, and medicinal chemistry. a comparative study of the synthesis of new bis-spiro-oxindolo(pyrrolizidines/pyrrolidines) ring systems by the cycloaddition of azomethine ylides generated by a decarboxylative route from sarc...
We propose a spectrum-dependent mechanism for the oxidation of 2,2',7,7'-tetrakis(N,N-di-p-methoxyphenylamine)-9,9'-spirobifluorene (Spiro-OMeTAD) with bis(trifluoromethane)sulfonimide lithium salt (LiTFSI), which is commonly used in perovskite solar cells as the hole transport layer. The perovskite layer plays different roles in the Spiro-OMeTAD oxidization for various spectral ranges. The eff...
The pattern of mannosyl lipid-linked oligosaccharides synthesized by cell-free enzyme preparations from cultured fibroblasts is altered substantially when 0.2 muM UDP-glucose is added to the incubation medium. Inclusion of UDP-glucose results in the appearance of a new labeled oligosaccharide, which is 1 or 2 glycose units larger than the lipid-linked oligosaccharide synthesized in the presence...
In both 3-tert-butyl-7,7-dimethyl-1-phenyl-5,6,7,8-tetrahydroimidazo[3,4-b]quinolin-5-one, C22H25N3O, (I), and 2,8,8-trimethyl-5-phenyl-6,7,8,9-tetrahydroimidazo[2,3-a]quinolin-6-one, C19H19N3O, (II), the heterobicyclic portions of the molecules are planar, with naphthalene-type delocalization in (II), while the carbocyclic ring in each compound adopts an envelope conformation. In both (I) and ...
Dihydroimidazo[5,1-c][1,2,4]triazine-3,6(2H,4H)-dione derivatives were prepared by successive N3- and N1-alkylation of hydantoins, followed by regioselective thionation and subsequent cyclization under mild conditions. In a final alkylation step a further substituent may be introduced. The synthetic strategy allows broad structural variation of this new drug-like heterobicyclic scaffold. In add...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید