Human KCNQ4 mutations known as DFNA2 cause non-syndromic, autosomal-dominant, progressive high-frequency hearing loss in which the cellular and molecular basis is unclear. We provide immunofluorescence data showing that Kcnq4 expression in the adult cochlea has both longitudinal (base to apex) and radial (inner to outer hair cells) gradients. The most intense labeling is in outer hair cells at ...

We describe in this paper two on-line algorithms for covering planar areas by a square-shaped tool attached to a mobile robot. Let D be the tool size. The algorithms, called Spanning Tree Covering (STC) algorithms, incrementally subdivide the planar area into a grid of D-size cells, while following a spanning tree of a grid graph whose nodes are 2D-size cells. The two STC algorithms cover gener...

We present a three dimensional model for the Milky Way fit to the farinfrared (FIR) and near-infrared (NIR) data from the COBE/DIRBE instrument for galactic latitudes |b| < 30 degrees and to within 20 degrees of the Galactic center. Because of the low optical depth at 240μm, the FIR emission traces the distribution of Galactic dust in the Galaxy. We model the dust distribution as due to three c...

We investigate a class of continuum models for the motion of a twodimensional biological group under the influence of nonlocal social interactions. The dynamics may be uniquely decomposed into incompressible motion and potential motion. When the motion is purely incompressible, the model possesses solutions which have constant population density and sharp boundaries for all time. Numerical simu...

conclusions the automatic bolus-tracking method, results in higher contrast enhancement of the aorta and spleen at the portal phase, but has no effect on liver enhancement. however, bolus tracking is associated with reduced variability for liver enhancement among different patients. results forty-eight patients (23 male, 25 female, mean age=56.4±13.5 years) were included. the contrast enhanceme...

We consider the underdamped dynamics of a chain of atoms subject to a dc driving force and a quasiperiodic substrate potential. The system has three inherent length scales which we take to be mutually incommensurate. We find that when the length scales are related by the spiral mean (a cubic irrational) there exists a value of the interparticle interaction strength above which the static fricti...

The spiral structure of the low surface brightness galaxies F568-6 (Malin 2) and UGC 6614 is large scale, with arms that wrap more than half a revolution, and extend out to 50 and 80 kpc in UGC 6614 and F568-6 respectively. The density contrasts observed in the H I maps are high, with arm/interarm contrasts of ∼2:1, whereas the velocity perturbations due to spiral structure are low, in the rang...

Some length-preserving operations on strings only permute the symbol positions in strings; such an operation X gives rise to a family {Xn}n≥2 of similar permutations. We investigate the structure and the order of the cyclic group generated by Xn. We call an integer n X-prime if Xn consists of a single cycle of length n (n ≥ 2). Then we show some properties of these X-primes, particularly, how X...

Pentagon–hexagon-patches are connected bridgeless plane graphs with all bounded faces pentagons or hexagons, all interior vertices of degree 3 and all boundary vertices of degree 2 or 3. In this paper we determine the minimum and maximum possible boundary lengths min (h, p) and max (h, p) of pentagon–hexagon-patches with h hexagons and p ≤ 6 pentagons and determine which intermediate values can...