BACKGROUND AND PURPOSE Polyglutamine expansion spinocerebellar ataxias are autosomal dominant slowly progressive neurodegenerative diseases with no current treatment. MR imaging is the best-studied surrogate biomarker candidate for polyglutamine expansion spinocerebellar ataxias, though with conflicting results. We aimed to review quantitative central nervous system MR imaging technique finding...

BACKGROUND AND PURPOSE The ability of DTI to track the progression of microstructural damage in patients with inherited ataxias has not been explored so far. We performed a longitudinal DTI study in patients with spinocerebellar ataxia type 2. MATERIALS AND METHODS Ten patients with spinocerebellar ataxia type 2 and 16 healthy age-matched controls were examined twice with DTI (mean time betwe...

We study degenerations of Grassmannians constructed using convex lattice configurations in Bruhat-Tits buildings. Using techniques from quiver representations, we analyze their special fibers, which are explicitly described as Grassmannians. For a class configurations, called the locally linearly independent show that our construction coincide with Mustafin degenerations, thus generalizing resu...

This is an expositiry article on collapsing theory written for the Modern Encyclopedia of Mathematical Physics (MEMPhys). We focus on describing the geometric and topological structure of collapsed/non-collapsed regions in Riemannian manifold under various curvature assumptions. Numerous applications of collapsing theory to Riemannian geometry are not discussed in this survey, due to page limit...

Developments in Ophthalmology Vol. 8 Series Editor W. Straub, Marburg a.d. Lahn KARGER S. Karger • Basel • München • Paris • London • New York• Tokyo • Sydney Hereditary Vitreoretinal Degenerations W. Lisch, Dortmund Translated by F. C. Blodi 31 figures, 5 cpl. and 1 table, 1983 KARGER S. Karger • Basel • München • Paris • London • New York • Tokyo • Sydney Developments in Ophthalmology Nationa...