نتایج جستجو برای: spinal cord injuries sci

تعداد نتایج: 275315  

Journal: :iranian biomedical journal 0
علیرضا عبدانی پور alireza abdanipour تقی طریحی taki tiraihi طاهر طاهری taher taheri هادی کاظمی hadi kazemi

background: the present study was designed to evaluate the secondary microglial activation processes after spinal cord injury (sci). methods: a quantitative histological study was performed to determine ed-1 positive cells, glial cell density, and cavitation size in untreated sci rats at days 1, 2, and 4, and weeks 1, 2, 3, and 4. results: the results of glial cell quantification along the 4900...

Journal: :iranian journal of basic medical sciences 0
arash sarveazad department of anatomy, faculty of medicine, iran university of medical sciences, tehran, iran mehrdad bakhtiari department of anatomy, faculty of medicine, iran university of medical sciences, tehran, iran asrin babahajian department of anatomy, faculty of medicine, tehran university of medical sciences, tehran, iran atusa janzade physiology research center, faculty of medicine, iran university of medical sciences, tehran, irandepartment of medical basic sciences, faculty of allied medicine, iran university of medical sciences, tehran, irandepartment of physiology, tehran, iran ali fallah systems and synthetic biology group, bioeconomy company, tehran, iran fatemeh moradi department of anatomy, faculty of medicine, iran university of medical sciences, tehran, iran

objective(s):spinal cord injury (sci) is one of the most serious clinical diseases and its treatment has been a subject of interest to researchers. there are two important therapeutic strategies in the treatment of sci: replacing lost tissue cells through cells implantation and scar elimination. therefore, in this study we used human adipose-derived stem cells (hadscs) implantation and injectio...

Abbas Piryaei, Arash Zaminy, Mohammad Ali Shokrgozar, Mohammad Hassan Heidari, Mohsen Noroozian, Yousef Sadeghi,

Background: Spinal cord has a limited capacity to repair therefore, medical interventions are necessary for treatment of injuries. Transplantation of Schwann cells has shown a great promising result for spinal cord injury (SCI). However, harvesting Schwann cell has been limited due to donor morbidity and limited expansion capacity. Furthermore, accessible sources such as bone marrow stem cells ...

Mahdi Safdarian Mahla Babaie Tahereh Ghadiri Vafa Rahimi-Movaghar, Zeynab Noorimotlagh,

Objective(s):To determine the molecular and cellular mechanisms of spinal cord regeneration in zebrafish. Materials and Methods: Medical databases of PubMed and Scopus were searched with following key words: Zebrafish; spinal cord injuries; regeneration; recovery of function. The map of mechanisms was performed using Xmind software. Results: Wnt/ß-catenin signaling, L1.1, L1.2, Major vault prot...

2018
Xiaodong Yan Juanfang Liu Xiji Wang Wenhao Li Jingyuan Chen Honghui Sun

Spinal cord injury (SCI) affects more than 2.5 million people worldwide. Spinal cord edema plays critical roles in the pathological progression of SCI. This study aimed to delineate the roles of aquaporin 4 (AQP4) and Na+-K+-Cl- cotransporter 1 (NKCC1) in acute phase edema and tissue destruction after SCI and to explore whether inhibiting both AQP4 and NKCC1 could improve SCI-induced spinal ede...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2015
Kaimeng Du Susu Zheng Qian Zhang Songshan Li Xin Gao Juan Wang Liwen Jiang Kai Liu

UNLABELLED Chronic spinal cord injury (SCI) is a formidable hurdle that prevents a large number of injured axons from crossing the lesion, particularly the corticospinal tract (CST). This study shows that Pten deletion in the adult mouse cortex enhances compensatory sprouting of uninjured CST axons. Furthermore, forced upregulation of mammalian target of rapamycin (mTOR) initiated either 1 mont...

2016
David J. Berlowitz Brooke Wadsworth Jack Ross

Spinal cord injury (SCI) is characterised by profound respiratory compromise secondary to the level of loss of motor, sensory and autonomic control associated with the injury. This review aims to detail these anatomical and physiological changes after SCI, and outline their impact on respiratory function. Injury-related impairments in strength substantially alter pulmonary mechanics, which in t...

Journal: :journal of modern rehabilitation 0
طاهره جهانگرد tahereh jahangard ph.d.student , department of physical therapy, faculty of medical sciences , tarbiat modares university.tehran,iranدانشجوی دکترای فیزیوترا،پی دانشکده علوم پزشکی، دانشگاه تربیت مدرس گیتی ترکمان giti torkaman department of physical therapy, faculty of medical sciences , tarbiat modares university.tehran,iranاستاد گروه فیزیوتراپی، دانشکده علوم پزشکی، دانشگاه تربیت مدرس مژده قبائی mojdeh ghabaee department of neurology, faculty of medical sciences .tehran university. tehran,iranدانشیار گروه داخلی مغز و اعصاب، دانشکده پزشکی، دانشگاه علوم پزشکی تهران

background and aim: the normal response of h-reflex depression (hd) was reduced in chronic spinal cord injury (sci) patients. the reduction of this normal response can lead to increase the muscle tone and spasticity. the purpose of this study is to investigate the effect of tripolar cathodal stimulation on hd in sci patients.   materials and methods: this study was conducted in 10 volunteered s...

Journal: :مجله علوم اعصاب شفای خاتم 0
sara abdolahi a. shefa neuroscience research center, khatam alanbia hospital, tehran, iran b. department of pathobiology, school of veterinary medicine, shiraz university, shiraz, iran zahra aeini shefa neuroscience research center, khatam alanbia hospital, tehran, iran robabeh jafari shefa neuroscience research center, khatam alanbia hospital, tehran, iran zeinab najmi microbial biotechnology group, faculty of basic sciences, tehran science and research branch, islamic azad university, tehran, iran maryam jafari department of parasitology and mycology, school of medicine, shiraz university of medical sciences, shiraz, iran ali jahanbazi jahan abad shefa neuroscience research center, khatam alanbia hospital, tehran, iran

spinal cord injury (sci) actuate to complex cellular and molecular interactions within the central nervous system in a heave to repair the initial tissue damage. the pathophysiology of acute spinal cord injury (sci) involves primary and secondary mechanisms. neuroinflammation is an important secondary injury process in sci. the local inflammatory microenvironment within the injured spinal cord ...

Fariborz Samini, Gholamreza Bahadorkhan, Hamed Kheradmand, Mohammadreza Ehsaei,

  Abstract   Objective: To evaluate and review our experience with pediatric spinal injuries and   factors affecting outcome, the authors conducted a retrospective clinical study of 43   cases (32 boys, 11 girls) of pediatric spine injuries treated during four years (January   1999 to December 2003).   Methods: Forty-three children with spinal injuries were studied retrospectively   over four y...

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