Severe pulmonary hypertension (SPH) is characterized by precapillary arteriolar lumen obliteration, dramatic right ventricular hypertrophy, and pericardial effusion. Our recently published rat model of SPH recapitulates major components of the human disease. We used this model to develop new treatment strategies for SPH. SPH in rats was induced using VEGF receptor blockade in combination with c...

The development of a methodology for the simulation of structure forming processes is highly desirable. The smoothed particle hydrodynamics (SPH) approach provides a respective framework for modeling the self-structuring of complex geometries. In this paper, we describe a diffusion-controlled phase separation process based on the Cahn-Hilliard approach using the SPH method. As a novelty for SPH...

The purpose of this study was to identify safe patient handling (SPH) curricular content in accredited occupational therapy and occupational therapy assistant programs in the United States of America. A survey was emailed to 155 accredited occupational therapy and 137 accredited occupational therapy assistant programs. With a 39% response rate, most programs addressed SPH curricula by including...

We monitored presynaptic exocytosis and vesicle recycling at neuromuscular junctions of transgenic mice expressing synaptopHluorin (spH), using simultaneous optical and electrophysiological recordings. Synaptic transmission was indistinguishable from that in wild-type controls. Fluorescence rose during and decayed monotonically after stimulus trains to the nerve, with amplitudes and decay times...

In order to modify the xanthan gum (XG) polysaccharide and to develop the hydrogels meant for the drug delivery, we have prepared XG-g-poly [HEMA-co-AA] superporous hydrogel (SPH) through chemical cross-linking by graft copolymerization of 2-hydroxyethyl methacrylate (HEMA) and acrylic acid (AA) on to XG via redox initiator system of ammonium persulfate (APS) and N, N, N’, N’tetramethylethylene...

Mathematical modeling of ice sheets is complicated by the nonlinearity of the governing equations and boundary conditions. Standard grid-based methods require complex front-tracking techniques and have a limited capability to handle large material deformations and abrupt changes in bottom topography. Consequently, numerical methods are usually restricted to shallow ice-sheet and ice-shelf appro...

BACKGROUND Self-perceived health (SPH) is a powerful indicator of the health status of elderly people. This issue has been widely studied in oldest populations considering altogether functionally independent and dependent individuals. The objective of this study was to describe SPH and to identify the main factors that have an impact on SPH in a sample of functionally independent community-dwel...

Objective: Sinistral, or left-sided, portal hypertension (SPH) is a rare cause of upper gastrointestinal hemorrhage. This retrospective analysis summarizes the clinical features of SPH and the results of surgical treatment. Subjects and Methods: Between 2000 and 2009, patients from our hospital diagnosed with SPH were identified. Diagnosis of SPH was based on evidence of isolated splenic vein t...

Iron is an important trace metal element in human body. Iron deficiency affects human health, especially pregnant women and children. Soybean protein is a popular food in Asia and contains a high amount of iron (145.70 ± 0.74 μg/g); however, it is usually reported as an inhibitor of iron absorption. In this study, the effect of hydrolysis on iron bioavailability of soybean protein was investiga...

We derive a new special-relativistic version of Smooth Particle Hydrodynamics (SPH) from the Lagrangian of an ideal fluid. The new formulation accounts for the terms that stem from non-constant smoothing lengths, in SPH usually called ”grad-h terms”. To handle shocks a refined artificial viscosity scheme is applied. The performance of this new equation set is explored in a variety of benchmark ...