نتایج جستجو برای: sperm rnas

تعداد نتایج: 70534  

Journal: :Human molecular genetics 2007
Adrian E Platts David J Dix Hector E Chemes Kary E Thompson Robert Goodrich John C Rockett Vanesa Y Rawe Silvina Quintana Michael P Diamond Lillian F Strader Stephen A Krawetz

We are coming to appreciate that at fertilization human spermatozoa deliver the paternal genome alongside a suite of structures, proteins and RNAs. Although the role of some of the structures and proteins as requisite elements for early human development has been established, the function of the sperm-delivered RNAs remains a point for discussion. The presence of RNAs in transcriptionally quies...

2016
Qiyuan Yang Jimin Lin Miao Liu Ronghong Li Bin Tian Xue Zhang Beiying Xu Mofang Liu Xuan Zhang Yiping Li Huijuan Shi Ligang Wu

Small RNAs play important roles in early embryonic development. However, their expression dynamics and modifications are poorly understood because of the scarcity of RNA that is obtainable for sequencing analysis. Using an improved deep sequencing method that requires as little as 10 ng of total RNA or 50 oocytes, we profile small RNAs in mouse oocytes and early embryos. We find that microRNA (...

Journal: :international journal of reproductive biomedicine 0
seppan prakash elumalai prithiviraj sekar suresh nagella venkata lakshmi mohanraj karthik ganesh murugesan anuradha

sperms are highly specialized cells for delivering dna from male to the ovum. incredibly, wide degree of diversity in sperm morphology in their basic structures i.e. head, middle piece and tail is found across species. differences in terms of overall size of the sperm, shape and number of sperm produced are also incredible. one of the key for this variations or diversity in sperm may be associa...

Journal: :Frontiers in Cell and Developmental Biology 2021

Spermatogenesis involves coordinated processes, including meiosis, to produce functional gametes. We previously reported Topaz1 as a germ cell-specific gene highly conserved in vertebrates. knockout males are sterile with testes that lack haploid cells because of meiotic arrest after prophase I. To better characterize –/– testes, we used RNA-sequencing analyses at two different developmental st...

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