evidence suggests that human sperm chromatin anomalies adversely affect reproductive outcomes and infertile men possess substantially amount of sperm with chromatin anomalies than fertile men. routine semen analysis evaluates parameters such as sperm motility and morphology, but does not examine the nuclear dna integrity of spermatozoa. it has been suggested that altered nuclear chromatin struc...

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. Recent studies show that spermatozoal DNA integrity is essential for normal fertilization and transmission of paternal genetic information to the offspring. Additionally, fertilization and embryo development depend on the sperm DNA structure (1,2). Generally, while fertile men have high levels of sperm with intact DNA...

BACKGROUND Smoking has a negative effect on fertility and sperm quality. This study was designed to evaluate the effects of smoking on sperm quality and the related parameters such as sperm concentration, morphology and motility. MATERIALS AND METHODS This cross-sectional study was conducted on 180 infertile men with at least one year history of idiopathic infertility, who admitted to the Avi...

To investigate the role of the 'male factor' in the pathogenesis of recurrent spontaneous abortion (RSA), especially sperm morphology abnormalities, 120 previously selected couples with unexplained RSA were studied for sperm parameters retrospectively and prospectively. The patients were subdivided into three subgroups, depending on their reproductive outcome during the 3 years of follow-up stu...

Aim: To investigate the prevalence of high levels of sperm DNA damage among men from infertile couples with both normal and abnormal standard semen parameters. Methods: A total of 350 men from infertile couples were assessed. Standard semen analysis and sperm chromatin structure assay (SCSA) were carried out. Results: Ninety-seven men (28% of the whole study group) had a DNA fragmentation index...

objective: this study aims to evaluate the protective effects of american ginseng administered by gastric intubation on sperm vital quality in adult male rats treated with cyclophosphamide (cp). materials and methods: in this experimental study, 28 adult male wistar rats were assigned to four groups, seven rats in each. the animals allocated to control, cp treated, ginseng treated and cp-ginsen...

BACKGROUND High rates of sub-fertility and adverse pregnancy outcomes were seen after age 40. In contrast to oogenesis, spermatogenesis continues in elderly men. OBJECTIVE To retrospectively study the impact of aging on semen parameters in male partners of infertile couples in the rural area of developing country over 10 years and to find out whether aging affects male factor fertility and va...

background: this case-control study was designed with the aim of evaluating the role of sperm, oxidative stress and dna damage in idiopathic recurrent pregnancy loss (irpl). this pilot study is the first study done on the indian population which reports the association between dfi, tac and ros in couples experiencing irsa. methods: twenty infertile men with a history of irpl and 20 fertile cont...

Honey bees are a keystone species, playing an important role in the food cycle. Improving honey bee reproduction will aid replacement of lost colonies. Fertility potential and reproductive health dependent on semen sperm quality. Current data drone parameters limited to volume, concentration, viability, assignment motility grade scores. The assessment is importance determine fertility colony he...