BACKGROUND Genome-wide gene expression analyses of tumors are a powerful tool to identify gene signatures associated with biologically and clinically relevant characteristics and for several tumor types are under clinical validation by prospective trials. However, handling and processing of clinical specimens may significantly affect the molecular data obtained from their analysis. We studied t...

uniaxial compressive strength (ucs) and elastic properties of rocks play a major and vital role for the design of any engineering structure. the specimen diameter size is one of the main factors that influencing on ucs, elasticity modulus and poisson’s ratio (e and υ). here, an attempt has been made to investigate the effect of specimen diameter size on ucs, e and υ. moreover, we studied the co...

A wide variety of body fluid specimens have been utilized for analysis for the presence of drugs of abuse. Urine has been and remains the most widely used body fluid specimen for routine testing for drugs of abuse, but several alternative specimens are establishing their place as suitable for drug testing. Hair, sweat, and oral fluid have reached a sufficient level of scientific credibility to ...

The endemic Australian genus Neodialineura Mann is revised to include 13 species. Three species are previously described: N. nitens (White) and N. saxatilis (White) from southern mainland Australia and Tasmania, and N. striatithorax Mann from eastern Australia. Ten species are described as new, including N. ataxia sp. nov., N. atmis sp. nov., N. bagdad sp. nov, N. bifaria sp. nov., N. litura sp...

background while tuberculosis (tb) can be diagnosed by microscopy and culture, the sensitivity of ziehl-neelsen staining is variable and culture results require 4 - 8 weeks to be determined. polymerase chain reaction (pcr) and its modifications, including nested pcr, might be promising methods for the rapid diagnosis of tb. objectives this study aimed to evaluate the performance of nested pcr o...

by drawing blood through a heparin lock, patients can be protected from skin damages duo to repeated needle sticks. in addition, this procedure can assist to gain more precise results in laboratory test and to prevent further complications. probably, you have ever used a heparin lock in order to infusion of medicines but, it is possible that you never use of that for blood sampling. both two pr...

BACKGROUND AND AIM The potential of microRNAs (miRNA) as non-invasive diagnostic, prognostic, and predictive biomarkers, as well as therapeutic targets, has recently been recognized. Previous studies have highlighted the importance of consistency in the methodology used, but to our knowledge, no study has described the methodology of sample preparation and storage systematically with respect to...

BACKGROUND Microfluidic-based systems are ideal for handling small microliter volumes of samples and reagents, but 'real-world' or clinical samples for bioanalysis are often on the milliliter scale. We aimed to develop and validate a large-volume centrifugal or compact disc-based device for blood plasma separation, capable of processing 2 ml undiluted blood samples. RESULTS This automated blo...