Violations of spatiotemporal continuity disrupt performance in many tasks involving attention and working memory, but experiments on this topic have been limited to the study of moment-by-moment on-line perception, typically assessed by passive monitoring tasks. We tested whether persisting object representations also serve as underlying units of longer-term memory and active spatial navigation...

background: multiple sclerosis (ms) is a disease of the immune system that creates damage of learning and memory in that. using probiotic supplements is recommended for preventing ms disease and improving memory. this study aimed to investigate the effect of lactobacillus plantarum (lp) and bifidobacterium b94 (bb94), on acquisition phase of spatial memory in the local demyelination of rats` hi...

introduction: alzheimer disease is a progressive and irreversible neuropsychiatric disorder. melissa officinalis improves anxiety and clinical dementia symptoms caused by ad therefore, the purpose of the present study was to evaluate the effect of mellisa extract on spatial memory deficit induced by stz in mwm examination of male wistar rats. methods: in the present study, 112 male wistar rats ...

Recent work with simulated reductions in visual acuity and contrast sensitivity has found decrements in survey spatial learning as well as increased attentional demands when navigating, compared to performance with normal vision. Given these findings, and previous work showing that peripheral field loss has been associated with impaired mobility and spatial memory for room-sized spaces, we inve...

BARLOW, STEVEN TODD. Spatial Knowledge Acquired Through Navigation In A LargeScale Virtual Environment. (Under the direction of Sharolyn Converse.) The effects of changes in elevation, route distance, route complexity, and non-spatial information on memory for a virtual environment were investigated. Thirty college students learned the layout of a two-story virtual environment through a series ...

We investigated how objects come to serve as landmarks in spatial memory, and more specifically how they form part of an allocentric cognitive map. Participants performing a virtual driving task incidentally learned the layout of a virtual town and locations of objects in that town. They were subsequently tested on their spatial and recognition memory for the objects. To assess whether the obje...

Prism adaptation (PA) is responsible for an expansion of sensori-motor after-effects to cognitive domains for patients with spatial neglect. One important question is whether the cognitive after-effects induced by PA may also concern higher aspects of spatial cognition, such as navigation and topographic memory, which are critical in everyday life. The aim of this study was to assess whether mu...

The current research sought to construct a computational model of human navigation for virtual three dimensional environments. The model was implemented within the ACT-R cognitive architecture [1]. The navigation model incorporates visual search, encoding object features and spatial relationships, motion, obstacle avoidance, and incidental visual memory.

The retrosplenial cortex (RSC) plays an important role in memory and spatial navigation. It shares functional similarities with the hippocampus, including the presence of place fields and lesion-induced impairments in spatial navigation, and the RSC is an important source of visual-spatial input to the hippocampus. Recently, the RSC has been the target of intense scrutiny among investigators of...

Patients with Alzheimer's disease (AD) frequently have difficulties with spatial orientation in their day-to-day life. Although AD is typically preceded by amnestic mild cognitive impairment (MCI), spatial navigation has not yet been studied in MCI. Sixty-five patients were divided into five groups: probable AD (n = 21); MCI, further classified as amnestic MCI single domain (n = 11); amnestic M...