birth of the son whose case is described below. Dimness of sight then came on, and gradually progressed to complete blindness without any redness, pain or lachrymation. An examination of the eyes gave the following results (28th April 1897) :? Right eye: The iris is divided completely into two portions (Fig. 1) by two large broad colobomata, one of which extends downwards and outwards, the othe...

Interactions between neurosteroids and GABA receptors have attracted particular attention in the supraoptic nucleus (SON). Although GABA(A) receptors (GABA(A)R) mediate a sustained tonic inhibitory current (I(tonic)), as well as conventional phasic inhibitory postsynaptic currents (IPSCs, I(phasic)) in the SON, whether the steroid modulation on I(tonic) is present in SON magnocelluar neurosecre...

We propose a theory of combinatorially explicit Schubert polynomials which represent the Schubert classes in the Borel presentation of the cohomology ring of the orthogonal flag variety X = SON/B. We use these polynomials to describe the arithmetic Schubert calculus on X. Moreover, we give a method to compute the natural arithmetic Chern numbers on X, and show that they are all rational numbers.

This paper concerned with applicability of the method of Kantorovich majorants to nonlinear singular integral equations with Hilbert kernel . The results are illustrated in Hölder space. RESUMEN Este art́ıculo es concerniente a la aplicabilidad del método de mayorantes de Kantorovich para ecuaciones integrales singulares no lineales con núcleo de Hilbert. Los resultados son aplicaciones en espac...

In-depth interviews with 30 sons actively involved in caring for a parent with dementia expand the understanding of sons' caregiving experiences. The within-group analysis revealed common themes that emerged from the narratives--duty, acceptance, taking charge, common emotions, and work flexibility--as well as common issues--loss, sibling relationships, role reversal, coping strategies, and pos...

Potassium channels are trans-membrane proteins, which selectively transport K+ ions across cell membranes and play a key role in regulating the physiology of excitability cells and signal transduction pathways. Bothutous Schach (BS) scorpion venom consists of several polypeptides that could modulate ion channels. In this study, the effects of BS crude venom on passive and active electrophysiolo...

To investigate the effects of novel intravenous general anesthetic propofol on membrane electrophysiological characteristics and action potential (AP) of the supraoptic nucleus (SON) neurons and possible ionic mechanisms, intracellular recordings were conducted in SON neurons from the coronal hypothalamic slice preparation of adult male Sprague Dawley (SD) rats. The results showed that bath app...

Noradrenaline and serotonin are known to control arginine-vasopressin (AVP) and oxytocin (OT) secretion in the systemic circulation. The aim of the current study was to investigate whether these monoamines are also able to influence AVP and OT expression in the paraventricular (PVN) and supraoptic nuclei (SON). To test this hypothesis, we used the Tg8 transgenic mice KO for the monoamine oxidas...