Selection pressures proposed to account for the convergent evolution of self/not-self recognition systems in lower organisms include defense against microbial parasites and somatic cell variants. Direct support for the existence of somatic cell parasites in natural populations has been lacking. I here report the occurrence of a somatic cell parasite in the cellular slime mold Dictyostelium muco...

regenerative capacity of mammals is limited and can rarely regenerate a specific organ or tissue fully. due to these limitations, regenerative medicine seeks efficient and safe cell sources for regeneration of damaged tissues and organs or treatment for incurable diseases. human embryonic stem cells (hescs) hold two important properties called self renewal and pluripotency. however, the use of ...

carcinogenesis is a multistep process characterized by the gradual accumulation of genetic changes that ultimately lead to cancer. these genetic mutations can impart limitless replicative potential to the cancer cells making them immortal. telomeres are repeat nucleotide sequence ttaggg that are present at the end of chromosomes. its functions are to protect the chromosomal ends and to ensure t...

plant tissue culture is an alternative method of commercial propagation and is being used widely for the commercial propagation of a large number of plant species, including many medicinal plants. somatic embryogenesis is a process by which asexual or somatic cells are induced to form embryos in culture. somatic embryogenesis is a multi-step regeneration process starting with formation of pro-e...

We have examined the distribution of histone H1 in oocytes and preimplantation embryos of the mouse, using a polyclonal antibody raised against the histone H1 subtypes present in somatic cells. Immunofluorescence and immunoblotting analyses failed to detect somatic histone H1 in germinal vesicle (GV)-stage oocytes. In contrast, somatic histone H1 was detectable by immunofluorescence in the nucl...