نتایج جستجو برای: soluble st2

تعداد نتایج: 90441  

2016
Jiayun Shen Qing Shang Chun-Kwok Wong Edmund K. Li Emily W. Kun Isaac T. Cheng Martin Li Tena K. Li Tracy Y. Zhu Cheuk-Man Yu Ling Qin Lai-Shan Tam

Psoriatic arthritis (PsA) patients have increased risk of both atherosclerosis and osteoporosis. Previous studies revealed that IL-33/ST2 axis may be related to both conditions; however, these associations were never evaluated in a single patients' group. Here we explored the association among plasma levels of IL-33 and its decoy receptor soluble ST2 (sST2), carotid plaque determined by ultraso...

Journal: :Journal of pharmacological sciences 2014
Takeshi Nabe

Interleukin (IL)-33, a member of the IL-1 family of cytokines, is produced when epithelial and endothelial cells are exposed to stimuli. Hematopoietic cells such as macrophages also produce IL-33. IL-33 is considered to function as an 'alarmin', activating various immune cells through its receptor ST2, which leads to the production of various molecules. The IL-33-induced production of pro-infla...

Journal: :The Journal of Experimental Medicine 1999
Katsuaki Hoshino Shin-ichiro Kashiwamura Kozo Kuribayashi Taku Kodama Tohru Tsujimura Kenji Nakanishi Tomohiro Matsuyama Kiyoshi Takeda Shizuo Akira

T1/ST2, an orphan receptor with homology with the interleukin (IL)-1 receptor family, is expressed constitutively and stably on the surface of T helper type 2 (Th2) cells, but not on Th1 cells. T1/ST2 is also expressed on mast cells, which are critical for Th2-mediated effector responses. To evaluate whether T1/ST2 is required for Th2 responses and mast cell function, we have generated T1/ST2-d...

2012
Karin Sahlander Kjell Larsson Lena Palmberg

Pig farmers are exposed to organic material in pig barns on a daily basis and have signs of an ongoing chronic airway inflammation and increased prevalence of chronic inflammatory airway diseases, predominantly chronic bronchitis. Interestingly, the inflammatory response to acute exposure to organic dust is attenuated in farmers. The aim of the study was to closer characterize innate immunity f...

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