UNLABELLED Background : The impact of the RECIST 1.1 on the selection of target lesions and assessment of tumor response was not evaluated in patients with advanced NSCLC who received cytotoxic chemotherapy. METHODS We reviewed medical records of patients with advanced NSCLC who received first-line chemotherapy between January 2004 and December 2013 and compared the selection of target lesion...

background: solid tumors may occur in 3% of the patients with chronic myeloid leukemia (cml). in this paper, we presented a case of cml following treatment of colon cancer. case presentation: a 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...

Background: Neuroblastoma is the most common extracranial solid tumor in children and the most common malignancy in infant.Some tumors release vasoactive intestinal peptide (VIP), causing a profound secretory diarrhea. In this report we describe a 33 month old girl with intermittent diarrhea from 9 month ago and hypokalemia resistant to treatment .She had increased VMA in 24hour urin .After co...

A better understanding of how solid malignancies arise in an immunocompetent host, avoid immune recognition, and ultimately progress to widely disseminated cancer is essential to effectively harness the immune system against solid tumors. Because of their extra-lymphatic localization, it has been proposed that solid malignancies are just ignored by the immune system, thereby allowing their unco...

testicular germ cell tumor (tgct) is the most solid tumor in 20-40 years old man. tgct account for 95% of testicular tumors and represent a unique type of human cancer from several different perspectives. tgct arise by transformation of germ cells. the transformed germ cells exhibit ploripotentially to differentiate into embryonic. extra-embryonic, and somatic tissue types, and are highly sensi...

introduction uterine leiomyomas are the most common benign solid tumors of the female pelvis. retroperitoneal myomas are extremely rare and usually malignant with the common location being in the pelvis. case presentation our case involved a woman who was suffering from dysparonia and radiculating right pelvic pain. the pelvic examination revealed a palpable tender mass of about 3-4 cm in size ...

Cyclin B1 is a key mitotic cyclin in the G2-M phase transition of the cell cycle and is overexpressed in various malignant tumors. Numerous studies have reported contradictory evidences of the correlation between cyclin B1 expression and prognosis in human solid tumors. To address this discrepancy, we conducted a meta-analysis with 17 published studies searched from PubMed and Medline. Cyclin B...

abstract objective tumors of the central nervous system constitute the largest group of solid neoplasms in children and are second only to leukemia in their overall frequency during childhood. the main purpose of the present study is to determine the incidence, age, sex, location and histological diagnosis of cns tumors in children, less than 15 years of age, in the mofid children's hospital, i...

Background: Solid tumors may occur in 3% of the patients with chronic myeloid leukemia (CML). In this paper, we presented a case of CML following treatment of colon cancer. Case Presentation: A 25 year old man was diagnosed of adenocarcinoma of rectosigmoid treated with fluorouracil-based chemotherapy. Following relapse, he received florouracil, oxaliplatin and irinotecan during the next year. ...