background bleaching of traumatized discolored teeth is considered an important issue in esthetic dentistry. various methods have been introduced for bleaching, some of which may have adverse effects on soft or hard tissues of the tooth. objectives the objective of the study was to evaluate the effects of ktp laser bleaching on enamel of traumatized teeth. materials and methods a square of 36 m...

in this paper, nickel oxide (nio) nanoparticles have been prepared by solid state thermal decomposition of an acyclic nickel(ii) complex (1,2-bis(2-formyl-3-methoxyphenyl)propane)nickel(ii) chloride, [nil]cl2, in an electrical furnace at optimal temperature, 450 ºc for 3.5 h. the nickel(ii) complex is obtained via solid state synthesis using nickel(ii) chloride and tetradentate o4 acyclic ligan...

context:in this review, we discuss empirical and stoichiometric models, which have been developed recently in ssf processes and the influence of environmental conditions on the variables of these models. additionally, new studies on modeling of product formation are also mentioned. evidence acquisition:solid-state fermentation (ssf) is recognized as a cheap process for producing many valuable p...

A major constraint in the treatment of cancer is inadequate oxygenation of the tumor mass, which can reduce chemotherapeutic efficacy. We hypothesize that polymerized human hemoglobin (PolyhHb) can be transfused into the systemic circulation to increase solid tumor oxygenation, and improve chemotherapeutic outcomes. By locking PolyhHb in the relaxed (R) quaternary state, oxygen (O2) offloading ...

Pyrrole-imidazole (Py-Im) polyamides can bind to the predetermined base pairs in the minor groove of double-helical DNA with high affinity. These synthetic small molecules can interfere with transcription factor-DNA interaction and inhibit or activate the transcription of corresponding genes. In the present study, we designed and synthesized a Py-Im polyamide to target -545 to -539 base pairs o...

A prototype of a novel class of DNA alkylating agents, which combines the DNA crosslinking moiety chlorambucil (Chl) with a sequence-selective hairpin pyrrole-imidazole polyamide ImPy-beta-ImPy-gamma-ImPy-beta-Dp (polyamide 1), was evaluated for its ability to damage DNA and induce biological responses. Polyamide 1-Chl conjugate (1-Chl) alkylates and interstrand crosslinks DNA in cell-free syst...

Pyrrole-imidazole polyamides are DNA-binding molecules that are programmable for a large repertoire of DNA sequences. Typical syntheses of this class of heterocyclic oligomers rely on solid-phase methods. Solid-phase methodologies offer rapid assembly on a micromole scale sufficient for biophysical characterizations and cell culture studies. In order to produce gram-scale quantities necessary f...

ZnO/activated carbon nanocomposites (ZnO/ACns) were synthesized by applying two different solid-state and precipitation methods. Precipitation method was initiated with zinc chloride and sodium hydroxide as starting materials in the presence of activated carbon. The synthesized sample was calcined at 250 °C for 1 h. The preparation of nanocomposite by solid-state method was accomplished by heat...

Thermoplastic polyamide elastomer (PAE) [also PEBA: polyether block amide] is one of the most recently developed of the thermoplastic elastomers: a multiblock polymer with polyamide hard segments, it uses longchain polyether diol or polyester diol of low Tg for its soft segments. Polyamide 6 or polyamide 12 (PA12) is the main polyamide component used, while the soft segments are mostly provided...