The effects of site-directed antibodies on single sodium channel currents in excised membrane patches from rat brain neurons have been examined. Of six antibodies directed against different intracellular domains of the sodium channel alpha subunit, only an antibody directed against a highly conserved intracellular segment between homologous transmembrane domains III and IV induced late single c...

The chromatographic behaviors of nucleotides (inosine 5'-monophosphate, uridine 5'-monophosphate, guanosine 5'-monophosphate, and thymine monophosphate disodium salts) on a C18 column were studied with different types of ionic liquids (ILs) as additives for the mobile phase in reversed-phase liquid chromatography (RPLC). Three ILs, 1-butyl-3-methylimidazolium tetrafluoroborate ([BMIm][BF4]), 1-...

We report densities, ijk ρ and speeds of sound, ijk u of 1-ethyl-3-methylimidazolium tetrafluoroborate (i) + water (j) + formamide or N,Ndimethylformamide (k) ternary mixtures over entire composition range at 293.15, 298.15, 303.15, 308.15 K. The heat capacities, Cpof 1-ethyl-3-methylimidazolium tetrafluoroborate, water, formamideand N,Ndimethylformamide have also been measured at 293.15, 298.1...

A new type of ratiometric fluorescent probe, 8-(diethylamino)-2-methyl-4-oxo-4H-pyrano[2,3-b] chromen-10-ylium tetrafluoroborate (APCT), is reported. A new type of ratiometric fluorescent probe, 8(diethylamino)-2-methyl-4-oxo-4H-pyrano[2,3-b]chromen-10-ylium tetrafluoroborate (APCT), is reported. This probe can successfully detect bisulfite anions with a detection limit of 6.1 10 7 M based on M...

To study the relalionship between Plasma Renin Activity (PRA), Plasma A1dost~one Concentralion (PAn and Urinazy Sodium Excretion iii 24 h voluma (UNaV), and Lo detcnnine Lhe prognosdc value of th~e vaiiables iii rdaticn to the r~ponse to sodium restnction, we studied 25 palients who had liva~ ciniiosis and non complicated ascites. A wi de vanation was found both in basal values and afta sodium ...

Esterification of naturally occurring hemins and porphyrins is often a prerequisite for structural studies of these compounds. Porphyrins and hemins are in general more easily purified as their esters than as the free carboxylic acids. In addition, esterification is the most feasible procedure for preparing derivatives of tetrapyrroles for studies by mass spectrometry. The most convenient and f...