An investigation of small intestinal electrolyte transport was performed in a subject with congenital chloridorrhoea using a constant perfusion technique. The results indicate that the diarrhoea was not due to an abnormally high rate of secretion of fluid into the duodenum, and transport of electrolytes and glucose was normal in the jejunum. In contrast there was a marked abnormality of electro...

BACKGROUND The use of hypertonic crystalloid solutions, including sodium chloride and bicarbonate, for treating severe sepsis has been much debated in previous investigations. We have investigated the effects of three crystalloid solutions on fluid resuscitation in severe sepsis patients with hypotension. METHODS Ninety-four severe sepsis patients with hypotension were randomly assigned to th...

Early dentifrices contained natural ingredients, mostly in coarse particle form, and were quite abrasive. Salts, either sodium chloride, sodium bicarbonate, or a mixture of both, have also been used for tooth cleaning because of their ready availability and low cost. Because of both their relatively low intrinsic hardness and their high solubility, another advantage is low abrasivity. Their big...

BACKGROUND Increased plasma potassium concentrations (K(+)) in neonatal calves with diarrhea are associated with acidemia and severe clinical dehydration and are therefore usually corrected by intravenous administration of fluids containing sodium bicarbonate. OBJECTIVES To identify clinical and laboratory variables that are associated with changes of plasma K(+) during the course of treatmen...

Using a triple-lumen constant perfusion system, the following observations were made in normal subjects. First, chloride, bicarbonate, and sodium were found to exhibit net movement across ileal mucosa against electrochemical gradients. Second, during perfusion with a balanced electrolyte solution simulating plasma, the ileum generally absorbed, but sometimes secreted fluid. A reciprocal net mov...

In previous studies, when rabbit cortical collecting ducts were studied under standard conditions in vitro, bicarbonate transport was conditioned by the acid-base status in vivo of the animals from which the tubules were obtained. The collecting ducts absorbed bicarbonate if the animals were acidotic (from ammonium chloride administration), but they secreted bicarbonate if the animals were alka...

The effects, on respiration, of the acute administration of sodium bicarbonate were studied in 10 normal subjects. Carbon dioxide responses curves and tidal volume v. PCO2 relationships were obtained under hyperoxic conditions using a closed-circuit breathing system. During alkalosis, a decrease in the slope, and a displacement of the response curves to the right, were observed. These findings ...

The suppressive effect of sodium and calcium salts applied individually or combined with the yeast Saccharomyces cerevisiae against Alternaria solani the causal agent of early blight disease of potato was evaluated under laboratory, greenhouse and field conditions. In vitro test a complete inhibition in fungal growth was observed at concentration of 30 mg/ml of both sodium bicarbonate and calci...

Darrow and his associates (1, 2) have recently obtained evidence that a correlation exists between the concentration of serum bicarbonate, muscle potassium, and intracellular sodium from a study on rats subjected to procedures designed to produce a deficit of one of the ions sodium, chloride, or potassium. Thus, the serum bicarbonate concentration was found to vary directly with the intracellul...