objective: asafoetida (ferula assa-foetida) is known as a valuable remedy for whooping cough, pneumonia, bronchitis in children and asthma treatment in folk medicine. in the present study the relaxant effects of the asafoetida on tracheal smooth muscle of guinea pigs and its probable mechanism(s) were examined. materials and methods: the relaxant effects of three cumulative concentrations of th...

objective(s): the study aimed to investigate the effects of adrenomedullin (adm) and proadrenomedullin n- terminal 20 peptide (pamp) on angiotensin ii (angii)-stimulated proliferation in vascular smooth muscle cells (vsmcs). materials and methods: thoracic aorta was obtained from wistar rats and vsmcs were isolated from aorta tissues and then cultured. in vitro cultured vsmcs were stimulated wi...

leiomyomas are benign tumors that originate from smooth muscle cells. leiomyomas are well known to be the commonest neoplasm arising from the uterus but leiomyomas originating from the scrotum is a rare entity. they originate from the subcutaneous tissue or tunica dartos and can be solitary or multiple. we present a case of solitary scrotal leiomyoma in a 75 years old male who presented with a ...

schwannomas are benign nerve sheath tumors that originate from any anatomical site. most of the schwannomas are found in the head, neck or limbs. schwannoma arising in a lymph node is extremely rare. we have found only four cases in the review of the literature. we experienced a case of intranodal schwannoma in a perigastric lymph node. a 72 year-old female underwent cholecystectomy due to clin...

The stimulatory effect of the extract of Portulaca oleracea (P. olerace) on β-adrenoceptor of tracheal smooth muscle was examined. To examine β-adrenoceptor stimulatory effect, concentration response curve to isoprenaline was obtained in pre-contracted tracheal smooth muscle in the presence of three concentrations of aqueous-ethanolic extract, propranolol and saline. Values of EC50 (the effecti...

Uterine smooth muscle tumors range from benign leiomyomata to low- and high-grade leiomyosarcomas. A leiomyosarcoma is a rare malignant smooth muscle tumor that infrequently metastasizes to the bone. In fact, initial presentation or recurrence as osseous metastases is extremely uncommon in patients with a history of leiomyosarcoma. On imaging, these bone lesions generally appear as lytic foci. ...

purpose: to assess the histopathological and immunohistochemical features of orbital spindle cell tumors. methods: a descriptive, retrospective study was performed on 63 pathology reports on all types of orbital spindle cell tumors at the pathology department of farabi hospital between 1995 and 2005. immunohistochemistry studies for different markers, such as smooth muscle actin, desmin, s100 p...

Perivascular epithelioid cell tumors (PEComa) are tumors of perivascular epithelioid cells with immunohistochemical features of smooth muscle and melanocytic tumors. The PEComa of the gastrointestinal tract is rare. The treatment is surgical, although there are data that suggest a good response to rapamycin.

The stimulatory effect of the extract of Portulaca oleracea (P. olerace) on β-adrenoceptor of tracheal smooth muscle was examined. To examine β-adrenoceptor stimulatory effect, concentration response curve to isoprenaline was obtained in pre-contracted tracheal smooth muscle in the presence of three concentrations of aqueous-ethanolic extract, propranolol and saline. Values of EC50 (the effecti...

Abstract Introduction: leiomyomas are benign mesenchymal tumors of smooth muscle origin that can develop in various locations. Urethral rare, with approximately only 120 cases reported the literature. These often occur third and fourth decades life but rare menopausal patients. In general, treatment involves surgery, three recurrence reports Description: a case report on 56-year-old woman; pati...