BACKGROUND AND OBJECTIVE The antipsoriatic effect of an innovative aerosol foam formulation of fixed combination calcipotriol 50 μg/g (as hydrate; Cal) and betamethasone 0.5 mg/g (as dipropionate; BD) was explored in order to compare the effect with that of the first-line treatment Cal/BD ointment. METHODS This was a Phase IIa, single-centre, investigator-blinded, exploratory study, with intr...

BACKGROUND Successful skin grafting requires multiple factors for success. An even distribution of constant pressure exerted upon the graft is necessary for successful graft take. It is well known that excessive pressure on a graft causes ischemia and may result in the failure of graft take. The aim of this study was to demonstrate the variation in skin pressure (tension) on curved surfaces, pa...

Foam is the natural phenomenon of bubbles that arise due to nucleation of gas in liquids. The current state of art in Computer Graphics rarely includes foam effects on large scales. In this paper we introduce a vertexbased, quasi-static equilibrium model from the field of Computational Physics as a new paradigm for foam effects. Dynamic processes like gas diffusion and bubble collapse are added...

BACKGROUND Polyurethane (PU) foam is widely used as a model for cancellous bone. The higher density foams are used as standard biomechanical test materials, but none of the low density PU foams are universally accepted as models for osteoporotic (OP) bone. The aim of this study was to determine whether low density PU foam might be suitable for mimicking human OP cancellous bone. METHODS Quasi...

Interaction of oxidized LDL (OxLDL) with macrophage-derived foam cells is one of the key events in the development and progression of atherosclerosis. To study this interaction, macrophage-derived foam cells were isolated from rabbit atherosclerotic lesions and the expression of scavenger receptors for OxLDL was examined. Atherosclerosis was induced in rabbits by denudation of the large arterie...

This study aimed to develop a modified Tessari method for producing more sclerosing foam in treatment of extensive venous malformations. Sclerosing foam was produced by using Tessari method and the modified Tessari method. The procedure of the later was as follows: prepared foam in a sclerosant-air ratio of 1:4; connected three disposable 10 ml syringes to two medical three-way taps; drawn 4 ml...

The concept of foam sclerotherapy was originally introduced by Orbach in 1944 who described the use of a froth made by shaking a syringe of sclerosant with air. He found that this was 10% more effective than the sclerosant used alone. Little was heard of this technique until Cabrera published an article in 1997 describing his experience in 261 limbs with long saphenous varices and 8 patients wi...

Thin metal films coated on soft elastomeric foam substrates exhibit enhanced electromechanical performance. The open-cell foam structure conveys highly anisotropic mechanical properties within the top, thin capping elastomer at the surface of the foam. Upon stretching, large strain fields inducing cracks and folds localize above the foam cells, while the surrounding cell ligaments remain almost...