An 8-year-old, male domestic shorthair cat was referred to the Matthew J. Ryan Veterinary Hospital of the University of Pennsylvania with a 3-day history of lethargy, inappetance, hyperemic skin nodules, coughing, and vomiting. Laboratory results included nonregenerative anemia, lymphopenia, thrombocytopenia, hypoalbuminemia, hyponatremia, and increased alanine aminotransferase and aspartate am...

We report a patient with multiple sclerosis (MS) who developed subcutaneous nodules in the face, shoulders and extremities while being treated with interferon (IFN)-β-1b. These nodules fluctuated in parallel with myelopathy, and were diagnosed as lupus erythematosus profundus (LEP) based on histopathological findings. The patient showed no relapse of either neurological symptoms or subcutaneous...

A 55-year-old man presented with generalized eczema and nodules. Physical examination revealed eczematous skin lesions on the face, trunk and extremities, with localized lichenification (Fig. 1A). Poikilodermatous skin changes were observed in the anterior neck and upper chest (Fig. 1B). In addition, numerous whitish dermal nodules 0.5–2 cm in diameter were observed on the trunk and extremities...

atypical mycobacterium granulomatous skin infections are often accured by mycobacterium marinum, m. ulcerans, m. fortuitum, and m. avium colonies. skin infections probably originate from an environmental source such as contacting with aquatic animals, fish farming and swimming in the pools, and inoculate into skin through skin wounds, scratches, trauma, and surgery. the lesions appear as purple...

Koebner phenomenon indicates the newly appearance of isomorphic lesions at the sites of mechanically stimulated or injured skin. This phenomenon can be seen in various inflammatory, auto-immune, viral, fibrotic, and even tumoral disorders. Also, rheumatic diseases such as lupus erythematosus, dermatomyositis, and rheumatoid arthritis (RA) often present with cutaneous manifestations with isomorp...

Pseudorheumatoid nodules are necrobiotic granulomas that are not associated with any systemic disease but that histopathologically mimic the granulomas of rheumatic fever, rheumatoid arthritis, and systemic lupus erythematosus [14] . Pseudorheumatoid nodules usually involve the skin of the extremities or scalp, but may occasionally involve the periocular area [5-7]. We report an unusual case of...

Mycobacterium marinum is an atypical mycobacterium that usually causes a solitary nodule on the hand ("fish tank granuloma") or less commonly, secondary erythematous channels and nodules spread along lymphatic drainage of the extremity, mimicking sporothricoid skin lesions of nodular lymphangitis. This report presents a case of this rare entity, a nodular lymphangitis caused by Mycobacterium ma...