The fastest and most effective way for a company to realize maximum profit is to get its pricing right. The right price can boost profit faster than increasing volume will; the wrong price can shrink it just as quickly. Yet many otherwise tough-minded managers miss out on significant profits because they shy away from pricing decisions for fear that they will alienate their customers. Worse, if...

Introduction: The government of Nepal has been providing free dialysis for a lifetime to its citizen since 2016. Most the patients have spend from pocket meet their medical demands sustain life. This leads financial burden and may lead sale property. aim this was study look into different categories expenses done by in Bipanna nagarik HD program provided Nepal.Materials Methods: descriptive cro...

Processes within the lowest several hundred kilometers of Earth's rocky mantle play a critical role in the evolution of the planet. Understanding Earth's lower mantle requires putting recent seismic and mineral physics discoveries into a self-consistent, geodynamically feasible context. Two nearly antipodal large low-shear-velocity provinces in the deep mantle likely represent chemically distin...

After retirement, the primary sources of uncertainty with respect to an individual’s economic status are longevity, investment outcomes and out-of-pocket spending on health care. In previous work, we estimated economic preparation for retirement, taking into account the risk of living to an advanced old age and the concomitant risk of running out of resources. But while we accounted for the ave...

The peptide binding site of HLA-B27 and other class I Ag consists of a series of pockets that bind peptide side chains. Two of these pockets interact with the amino-terminal peptide residue (pocket A) and with the highly conserved second residue (pocket B). In this study, the role of pockets A and B in HLA-B27-specific T cell allorecognition has been analyzed. Four HLA-B27 mutants with single o...

Countries with universal or near universal access to healthcare have health financing mechanisms which are single-payer systems in which either a single autonomous public agency or a few coordinated agencies pool resources to finance healthcare. This contributes to both equity in healthcare as well as to low levels of poverty in these countries. It is only in countries like India and a number o...

Attachment level or pocket depth measurements are used to detect change in periodontal attachment. However, measurement error limits their usefulness for this purpose. The aims of this study are twofold. The first aim was to test the assumption, used in previous reports of measurement error, that attachment level measurements are normally distributed. The second aim was to estimate error rates ...

The Poraniidae (Asteroidea, Valvatacea) is recorded for the first time from Australian waters at deep-sea (>200m) depths, including, present, Australia’s deepest known asteroid occurrence 3850 m. Three genera are reviewed, each represented by a single species, Poraniomorpha tartarus n. sp., Marginaster paucispinus Fisher 1913, and patriciae McKnight 2006, which reassigned to new genus, Bathy...