The present study reports the development and application of a flow injection analysis (FIA) system for simultaneous determination uric acid (UA) caffeine (CAF) using cathodically pretreated boron-doped diamond electrode (CPT-BDD) multiple-pulse amperometry (MPA). electrochemical profiles UA CAF were analyzed via cyclic voltammetry in potential range 0.20–1.7 V 0.10 mol L−1 H2SO4 solution as su...

purpose: one of the major causes of visual acuity loss in diabetic patients is diabetic macular edema (dme). best-corrected visual acuity and central macular thickness changes are considered as two main outcomes in diabetic macular patients. the goal of this study was to compare the effect of intravitreal bevacizumab injection alone or combined with triamcinolone versus macular photocoagulation...

Activated cyclophosphamides such as 4-sulfoethylthiocyclophosphamide (mafosfamide) are suitable for a local intracavitary chemotherapy, whereas cyclophosphamide requires a metabolic activation. Mafosfamide administered i.p. in mice was less toxic (50% lethal dose, 640 mg/kg) than its i.v. application (50% lethal dose, 480 mg/kg). A further remarkable reduction of toxicity with an increase of th...