A simple and rapid method has been developed for the determination of ascorbic acid in fruit and pharmaceutical products. The method is based on the measurement of the reaction rate between ammonium molybdate and ascorbic acid in acidic media. The reaction was monitored spectrophotometrically at 800 nm by fixed-time and variable-time methods. The calibration graph was linear in the range of...

This work reports a facile sonochemical route in the synthesis of nano particle of deferasirox for the first time. One application of nanotechnology is in improvement of available treatments for various diseases. Deferasirox (ICL670 or Exjade) is a tridentate chelating agent for removing transfusion overload iron in thalassemia patients. In the present work, deferasirox was prepared in nano size...

This work reports a facile sonochemical route in the synthesis of nano particle of deferasirox for the first time. One application of nanotechnology is in improvement of available treatments for various diseases. Deferasirox (ICL670 or Exjade) is a tridentate chelating agent for removing transfusion overload iron in thalassemia patients. In the present work, deferasirox was prepared in nano size...

a facile and efficient protocol for the synthesis of 1,8-dioxo-octahydroxanthenes has been developed by one-pot knoevenagel condensation, michael addition and cyclodehydration reaction of dimedone (active methylene carbonyl compound) with aromatic aldehydes in the presence of iron (iii) sulfate hydrate as a solid acidic catalyst under solvent-free conditions. various aromatic aldehydes were uti...

in this research, (carboxy-3-oxopropylamino)-3-propylsilylcellulose (copapsc) as an organocatalyst, has been synthesized by grafting of succinic anhydride on the nh2-modified cellulose (cellulose functionalized with 3- aminopropyltriethoxysilane). the –co2h group-functionalized cellulose (copapsc) is used as a catalyst for the synthesis of coumarin derivatives from the reaction of phenolic subs...

     In this study an easy, green, efficient and simple approach is reported for the synthesis of some benzothiazole-, benzimidazole- and benzoxazole-2-thiolderivatives. The proposed approach employs the reaction of corresponding aromatic amine with potassium isopropyl xanthate (Z11) in the presence of copper sulfate (CuSO4) as a catalyst under conventional heating and ultrasonic irr...

A simple and ecofriendly method was developed for the synthesis of arylmethylene[bis(5,5- dimethyl-3-hydroxy-2-cyclohexene-1-ones)] from the reaction of 5,5-dimethylcyclohexane- 1,3-dione and aromatic aldehydes in an aqueous media without any catalyst via Knoevenagel condensation followed by rapid Michael addition. No cyclization product was down to convert these enolic forms to xanthene deriva...

a highly efficient, simple and clean solvent-free protocol for the synthesis of polyhydroquinolines is described. the one-pot multi-component condensation reaction between arylaldehydes, dimedone (5,5-dimethylcyclohexane-1,3-dione), β-ketoesters and ammonium acetate in the presence of catalytic amount of (2.5 mol%) melamine trisulfonic acid (mtsa) as a recyclable, green and attractive sulfonic ...