This paper presents the implementation of a crossbar-based CIOQ switch with a novel matching algorithm that can be used for efficient interprocessor communication. The proposed matching algorithm, called SIM, uses a sequential mode to replace the traditional parallel mode to improve the efficiency of iterative matching operation. Moreover, the paper presents a FIFO-based request scheduler for t...

3-Hydroxy-3-methylglutaryl CoA reductase inhibitors decrease cardiovascular morbidity in diabetic patients, but the mechanism is unclear. We studied the actions of simvastatin (SIM) in enhancing NO bioavailability and reducing oxidative stress in coronary vessels from diabetic rats and in rat coronary artery endothelial cells (RCAEC) exposed to high glucose. Coronary arteries isolated from diab...

SIM-Lite is an astrometric interferometer being designed for sub-microarcsecond astrometry, with a wide range of applications from searches for Earth-analogs to determining the distribution of dark matter. SIM-Lite measurements can be limited by random and systematic errors, as well as astrophysical noise. In this paper we focus on instrument systematic errors and report results from SIM-Lite’s...

BACKGROUND Simvastatin increases the expression of bone morphogenetic protein 2 (BMP-2) in osteoblasts, therefore it is important to investigate the influence of statins on bone formation, fracture healing and implant integration. The aim of the present study was to investigate the effect of simvastatin, locally applied from intramedullary coated and bioactive implants, on bone integration usin...

Effects of green tea extract (GTE) on the activity of cytochrome P450 (CYP) enzymes and pharmacokinetics of simvastatin (SIM) were investigated in rats. Inhibitory effects of GTE on CYP3A activity were investigated in rat hepatic microsomes (RHM) using midazolam (MDZ) 1'-hydroxylation as a probe reaction. SD female rats received a single oral dose of GTE (400 mg/kg) or troleandomycin (TAO, a CY...

Mobile networks security is constantly evolving and adapting to meet the needs of users and network operators. It is a requirement that there be interoperation of legacy security frameworks into modern mobile networks. Mobile networks originally had no real security which proved to be a deployment that was attacked constantly and the providers were defrauded of millions of dollars. To address t...

The single-minded (sim) gene of Drosophila encodes a nuclear protein that plays a critical role in the development of the neurons, glia, and other nonneuronal cells that lie along the midline of the embryonic CNS. Using distinct cell fate markers, we observe that in sim mutant embryos the midline cells fail to differentiate properly into their mature CNS cell types and do not take their appropr...