Importance: Silica dust has long been known as an occupational hazard, primarily causing pulmonary fibrosis. There is a higher incidence of neoplastic diseases associated with silica exposure, mainly lung cancer. Observation: We present a unique case of a patient with pulmonary silicosis who developed diffuse lymphadenopathy followed by features of plasma cell proliferation with B lymphocyte mo...

Silicosis is considered to be among the occupational lung diseases and associated with sandblasting, mining, quarrying and tunneling. Acute silicosis is usually progressive diseaseand despite treatment with corticosteroids it leads to cardio-respiratory failure and death. Alveolar silicoproteinosis is one of it's acute presentations due to exposure to silica dust and lungs filling with proteina...

Silicosis is a form of pneumoconiosis caused by inhalation of crystalline silica dust, and is marked by inflammation and scarring in forms of nodular lesions in the upper lobes of the lungs. Silicosis (especially the acute form) is characterized by shortness of breath, fever, and cyanosis (bluish skin). It may often be misdiagnosed as pulmonary edema (fluid in the lungs), pneumonia, or tubercul...

Silicosis is the most common occupational lung disease worldwide. It leads to respiratory impairment and may have associated infections that decrease pulmonary function. We describe the case of a 55-year-old man with chronic silicosis who presented with hemoptysis and a cavitated conglomerate mass. The final diagnosis was silicotuberculosis.

UNLABELLED In our country quartz is widely used for denim sandblasting and new cases with silicosis are defined. Silicosis is a preventable occupational lung disease caused by inhaled dust containing crystalline silica and no effective treatment for silicosis is available (1). CASE 1: A 23-years old man was admitted to the hospital with dyspnea on effort and cough. He had worked in a denim manu...

Background: Silicosis is an irreversible progressive lung disease which leads to ultimate death. This study aimed to describe characteristics of individuals affected by silicosis, evaluate the prevalence of silicosis in miners and also introduce preventive policies. Materials and Methods: Cases with pathologic diagnosis of silicosis were retrieved from archive of pathology department of nationa...

The granite industry in Cornwall and Devon is briefly described, especially the production of dust in dressing the stone. In 1951, 210 granite masons were examined (about 84% of the total at that time) and 37 (17 6%) showed silicosis. These men were followed up for 10 years. No silicosis was seen in men with less than 15 years' exposure, but after this time the risk increased to 11 out of 14 in...

Silicosis is associated with fibroblast proliferation and extracellular matrix deposition in lung tissues. The dysregulation of miR-1224-5p has been implicated in several human cancers; however, the expression and function of miR-1224-5p in silicosis is unknown. The mitochondrial dysfunctions play critical roles in some diseases, but how these processes are regulated in silicosis remains limite...

Introduction: Silicosis is a progressive, fibrotic and preventable occupational lung disease. Occupational exposure in stone crushing units to silica particles of size 0.5 to 5μm poses a hazard to the workers. Methods: Our study is a passive surveillance study of silicosis in the symptomatic workers referred from Occupational Disease Centre to Department of Radiodiagnosis for chest X-Ray and Hi...