Sickle cell disorder is the most important genetic haematological disease that affects the people of black African descent. About 2% of all babies born to Nigerian parents have sickle cell anaemia (1). The distribution of indigenous sickle cell disorder coincides with the distribution of falciparum malaria. Possession of sickle cell trait confers a natural protection against death from malaria ...

By SAMUEL CIIARAcIIE AND C. LOCKARD CONLEY S ICKLED ERYTHROCYTES are rapidly removed for the circulation, an occurrence that accounts for the hemolytic aspects of sickle cell disease.’ Anemia is a usual result but is often asymptomatic and is not the principal cause of the high morbidity and reduced life span of affected persons. Many of the clinical manifestations of sicklemia have been attrib...

Abstract Background Prevalence of hereditary blood diseases such as sickle cell anemia, sickle thalassemia and thalassemia major are high in Khuzestan province. Sickle cell anemia and beta-thalassemia are predominantly common in Iranian Arabs. Pulmonary complications account for a large proportion of morbidity and mortality in patients with and sickle cell disease. Periodic lung function asse...

We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact that it is associated with significant morbidity such as renal papillary necrosis and renal medullary carcinoma. Appropriate evaluation needs ...

Sickle cell trait is a relatively common condition in the African-American population. Individuals with this condition may have any of several complications under rare circumstances. We report a patient who presented with extensive compartment syndrome leading to death. A 31-year-old African-American male with known history of sickle cell trait developed extensive compartment syndrome followed ...

The Sickle Cell Disease or the Sickle cell anemia common genetic disease affects millions of people worldwide. Many Soliga tribals suffer from the genetic disorder of the Sickle Cell Disease, 4.2% of the Soligas have AS type of Sickle cell trait (heterozygous), 0.2% of the Soligas have the Sickle cell anemia (homozygous), and the remaining 95.6% of the Soligas have normal haemoglobin, Tradition...

on determinations of hemoglobin A1c by an immunoassay method. Diabetes Care 1998;21:983–6. 6. Roberts WL, Chiasera JM, Ward-Cook KM. Glycohemoglobin results in samples with hemoglobin C or S trait: a comparison of four test systems. Clin Chem 1999;45:906–9. 7. Eckman JR. The Sickle Cell Foundation of Georgia, Inc. The Sickle Cell Information Center. http://www.emory.edu/PEDS/SICKLE/hemoglb.htm ...