BACKGROUND Systemic lupus erythematosus is an age- and gender-associated autoimmune disorder. Previous studies suggested that defects in the hypothalamic/pituitary axis contributed to systemic lupus erythematosus disease progression which could also involve growth hormone, insulin-like growth factor-1 and somatostatin function. This study was designed to compare basal serum growth hormone, insu...

BACKGROUND The neurobiological basis of autism remains poorly understood. The diagnosis of autism is based solely on behavioural characteristics because there are currently no reliable biological markers. To test whether the anterior pituitary hormones and cortisol could be useful as biological markers for autism, we assessed the basal serum levels of these hormones in subjects with autism and ...

Objective: To evaluate the prevalence of vitamin D deficiency in postmenopausal women light restrictions imposed by Covid-19 pandemic.Methods: This was a single-center cross-sectional study with total 167 patients (post-menopausal :133, pre-menopausal: 24) who were divided into two groups according to age.Result: There significant negative links between serum T4 hormone levels and each calcium ...

background: b-thalassemia major is a serious medical problem. growth retardation is commonly seen in poly-transfused b- thalassemia patients. the exact mechanism of short stature in children with thalassemia major is not well understood, however, it is believed to be multi-factorial. objective: to study the growth state and its relationship to growth hormone (gh) deficiency in b-thalassemia pat...

physiological mediators of human host such as androgenic hormones interfere pathogenic fungal growth. it has been revealed that the growth of yeasts as well as of dermatophytes is influenced by human androgenic hormones in vitro. in this reason for in vivo condition, the andrgenic hormones level must be measured in patients with dermatophytosis and healthy individuals. to this purpose we measur...

background: the influence of hashimoto’s thyroiditis (ht) with subclinical hypothyroidism or euthyroid status on the alteration of glucagon-like peptide (glp)-1 and glp-2 levels remains uncertain. materials and methods: twenty-four untreated ht patients with subclinical hypothyroidism, 24 euthyroid ht patients, and 24 age- and gender-matched controls were enrolled in the study. the levels of gl...

OBJECTIVE Tamoxifen has been used to prevent the recurrence of breast cancer. However, tamoxifen-users frequently experience amenorrhea and it can be confused from that caused by other hormonal abnormalities. In amenorrheic patients without breast cancer, clinicians usually measure the sex hormone levels that are known to be associated with ovarian or menstrual function. This study aimed to inv...

BACKGROUND AND PURPOSE The aim of this study was to determine if circulating levels of pituitary hormones are altered by stroke and, if so, whether these alterations offer insight into specific neurochemical pathways in the region of the central nervous system injury. METHODS Twenty-eight consecutive postmenopausal women undergoing computed tomographic imaging of the brain for evaluation of c...