EFFECT OF ISCHAEMIA ON SEROTONIN NEURONES IN THE RABBIT RETINA. CAZEVIEILLE C. and OSBORNE N.N. Nuftield Laboratory of Ophthalmology, University of Oxford, Oxford OX2 6AW, 1J.K. Serotonin is normally not present in sufficient concentrations in the rabbit retina for localisation by inununohistrxhemisby. The amine is taken up by a population of amacrine cells in the intact retina and in primary r...

In this article we report that the distribution of serotonin in the lobster nervous system parallels the distribution of octopamine and that the same tissues that contain endogenous serotonin can synthesize it from tryptophan. Octopamine and serotonin are highly concentrated in a neurosecretory region of the second thoracic roots in association with a group of neurosecretory cells. The roots po...

EFFECT OF ISCHAEMIA ON SEROTONIN NEURONES IN THE RABBIT RETINA. CAZEVIEILLE C. and OSBORNE N.N. Nuftield Laboratory of Ophthalmology, University of Oxford, Oxford OX2 6AW, 1J.K. Serotonin is normally not present in sufficient concentrations in the rabbit retina for localisation by inununohistrxhemisby. The amine is taken up by a population of amacrine cells in the intact retina and in primary r...

Post-feeding diuresis in Rhodnius prolixus is neurohormonally controlled by serotonin and at least one peptidergic diuretic hormone (possibly a CRF-related peptide). These appear to be released by two different neurosecretory groups – 5 dorsal unpaired median (DUM) cells and 5-6 lateral neurosecretory cells of the mesothoracic ganglionic mass. The DUM cells co-localize serotonin and the calcito...

Serotonin has a multifunctional role in many different organs serving either as a neurotransmitter in the central nervous system or a paracrine factor in the gastrointestinal tract. Over 90% of serotonin is synthesised in the enterochromaffin cells of the intestine and subsequently taken up by platelets. The involvement of platelet-derived serotonin in liver mass restoration after partial hepat...

carcinoid tumor is a slow-growing type of neuroendocrine tumor, originating in the enterochromaffin cells and secreting mainly serotonin. the diagnosis is based on clinical symptoms, hormone levels, radiological and nuclear imaging, and histological confirmation. the clinical symptoms are characterized by flushing, diarrhea, abdominal pain, telangiectasia and/or bronchoconstriction. however, mo...

We studied binding of serotonin to protein(s) derived from rat basophil leukemia (RBL) cells and mast cells. We found two types of serotonin binding protein in RBL cells. These proteins differed from one another in molecular weight and eluted in separate peaks from sephadex G-200 columns. Peak I protein (KD = 1.9 X 10(-6) M) was a glycoprotein that bound to concanavalin A (Con A); Peak II prote...

Serotonin is a vasoactive substance that in different blood vessels mostly induces vasoconstriction. Considering the important role of common carotid artery in brain blood supply, the aims of this study were to investigate the effect of serotonin on isolated rat common carotid artery and also to examine participation of intact endothelium, cyclooxygenase products, Ca(++) channels and 5-HT(2) re...

UNLABELLED The great many hormones released by the endocrine cells of the glands and lining epithelium of gastric mucosa determine its significance for the processes in the gastrointestinal tract. One of these hormones, serotonin, plays an important role in the regulation of the motility, secretion and sensation in the gastrointestinal tract. The aim of the present study was to conduct immunohi...