نتایج جستجو برای: serial resistance
تعداد نتایج: 431177 فیلتر نتایج به سال:
Weiss, Emilio (Naval Medical Research Institute, Bethesda, Md.) and Harry R. Dressler. Increased resistance to chloramphenicol in Rickettsia prowazekii with a note on failure to demonstrate genetic interaction among strains. J. Bacteriol. 83:409-414. 1962.-A further effort to produce genetically labeled Rickettsia prowazekii was made by serially passing the Madrid E strain in eggs in the presen...
Daptomycin resistance in Staphylococcus aureus emerged during therapy of tricuspid endocarditis. Susceptibility to daptomycin of the parent strain (SA-675), other daptomycin-susceptible strains and the non-susceptible mutant (SA-684) was heterogeneous; however, subpopulations growing at concentrations above the minimum inhibitory concentration (MIC) were not stably resistant. Stable resistance ...
With asymptotic and numerical analyses, we systematically study the influence of slip length and access Ohmic resistance (due to pore-end field focusing and concentration polarization) on the energy conversion efficiency of pressure-driven electrolyte flow through a charged nanopore. Hydrodynamic slip reduces the percent of energy dissipated by viscous dissipation but, through electro-osmotic c...
Resistance to the Bruton's tyrosine kinase (BTK) inhibitor ibrutinib has been attributed solely to mutations in BTK and related pathway molecules. Using whole-exome and deep-targeted sequencing, we dissect evolution of ibrutinib resistance in serial samples from five chronic lymphocytic leukaemia patients. In two patients, we detect BTK-C481S mutation or multiple PLCG2 mutations. The other thre...
Trastuzumab (Herceptin®) is a humanized monoclonal antibody designed to bind and inhibit the function of the human epidermal growth factor receptor 2 (HER2)/erbB2 receptor. Trastuzumab has demonstrated clinical activity in several types of HER2-overexpressing epithelial tumors, such as breast and metastatic gastric or gastroesophageal junction can...
background: metronidazole is drug of choice recommended by who for treatment of trichomoniasis, however, some reports claims drug resistance in trichomonas vaginalis isolates recently. the objective of this study was to determine the minimum lethal concentration (mlc) of metronidazole in resistant and sensitive strains, as well as genetic patterns of these stains by pcr method. methods : from f...
1 How many events? A key observation about serial verb constructions (SVCs) is that they express a single, perhaps complex, event rather than a series of distinct events a single serial verb complex describes what is conceptualized as a single event: this is repeatedly reported to be a clear intuition of native speakers, and can be demonstrated through semantic analysis. It follows that a seria...
This paper reports a serial dilution microfluidic network composed of microchannels with a high fluidic-resistance ratio for generating linear concentration profiles as well as logarithmic concentration profiles spanning 3 and 6 orders of magnitude. The microfluidic networks were composed of thin fluidic-resistance microchannels with 160 to 730 microm(2) cross-sectional areas and thick diffusio...
Analysing the consequences of the decrease in biodiversity for ecosystem functioning and stability has been a major concern in ecology. However, the impact of decline in soil microbial diversity on ecosystem sustainability remains largely unknown. This has been assessed for decomposition, which is insured by a large proportion of the soil microbial community, but not for more specialized and le...
BACKGROUND To develop a low cost method to screen for virologic failure of antiretroviral therapy (ART) and HIV-1 drug resistance, we performed a retrospective evaluation of a screening assay using serial dilutions of HIV-1 RNA-spiked blood plasma and samples from patients receiving >6 months of first-line ART. METHODS Serial dilution testing was used to assess sensitivity of a simple PCR-bas...
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