Rapid sensory detection of X-ray stimulation has been documented across a wide variety species, but few studies have explored the underlying molecular mechanisms. Here we report discovery an acute behavioral avoidance response in wild type Caenorhabditis elegans to stimulation. The endogenous C. UV-photoreceptor protein LITE-1 was found mediate locomotory response. Transgenic expression muscle ...

The initial cephalic phase of insulin secretion is mediated through the vagus nerve and not due to glycemic stimulation pancreatic ?-cells. Recently, IL-1? was shown stimulate postprandial secretion. Here, we describe that this incretin-like effect involves neuronal transmission. Further found release by originating from long-lived CX3CR1+ myeloid cells. Moreover, activated induce regulated act...

Primary open-angle glaucoma is a group of optic neuropathies that can lead to irreversible blindness. Sensory stimulation in the form of acupuncture or ear acupressure may contribute to protecting patients from blindness when used as a complementary method to orthodox treatment in the form of drops, laser or surgery. The objective of this article is to provide a narrative overview of the availa...

Invariant sensory coding is the robust coding of some sensory information (e.g., stimulus type) despite major changes in other sensory parameters (e.g., stimulus strength). The contribution of large populations of neurons (ensembles) to invariant sensory coding is not well understood, but could offer distinct advantages over invariance in single cell receptive fields. To test invariant sensory ...

UNLABELLED Spreading depolarizations (SDs) are recognized as actors in neurological disorders as diverse as migraine and traumatic brain injury (TBI). Migraine aura involves sensory percepts, suggesting that sensory cortices might be intrinsically susceptible to SDs. We used optical imaging, MRI, and field potential and potassium electrode recordings in mice and electrocorticographic recordings...

Embedded in everyday practices, food can be a rich resource for interaction design. This article focuses on eating experiences to uncover how bodily, sensory, and socio-cultural aspects of better leveraged the design user experience. We report systematic literature review 109 papers, interviews with 18 professional chefs, providing new understandings prior HFI research, as well chefs creatively...

OBJECT The aim of this study was to evaluate different types of sensory stimulation used to distinguish between microvasculature and venous drainage on functional magnetic resonance (fMR) images with blood oxygen level-dependent (BOLD) contrast. METHODS Seven volunteers received three sensory stimulations. One consisted of small discontinuous automated pokes to the ventral aspect of the right...

In the mammalian brain, calcium signals in dendritic spines are involved in many neuronal functions, particularly in the induction of synaptic plasticity. Recent studies have identified sensory stimulation-evoked spine calcium signals in cortical neurons in vivo. However, spine signaling during ongoing cortical activity in the absence of sensory input, which is essential for important functions...