Purpose To compare the effects of dexmedetomidine (Dex) and fentanyl as adjuvants to local anesthetics in spinal anesthesia. Methods Two researchers independently searched the PUBMED, EMBASE, Cochrane library, and CBM for randomized controlled trials comparing the effects of Dex and fentanyl as adjuvants to local anesthetics for intrathecal injection. Results A total of 639 patients from ni...

BACKGROUND The purpose of the present study is to investigate the anesthetic effect of reduced doses of spinal bupivacaine with epidural top ups in comparison with those of spinal bupivacaine and to determine the adequate doses of drugs used during lower extremity surgeries. METHODS SIXTY ADULT PATIENTS WERE RANDOMIZED TO THREE DIFFERENT TECHNIQUE GROUPS: S group (10 mg of spinal bupivacaine)...

A more posterior approach for abdominal wall blocks was described by Dr. Blanco as Quadratus Lumborum (QL) block. We performed the first reported transmuscular QL block using liposomal bupivacaine. We are describing the technique we used as well as other approaches used for QL block. This case report showed that QL block using a single dose of Liposomal Bupivacaine provided a sensory level and ...

Objective: In order to prolong the duration of intrathecal lidocaine, various drugs are used along with it. Due to the promising effects of tizanidine on central nervous system, it can be assumed that tizanidine can have a positive effect on increasing the anesthesia duration too. Thus, we aimed to investigate the effect of oral tizanidine on the duration of lidocaine spinal anesthesia.Me...

BACKGROUND Neuroaxial blockade for ambulatory transurethral resection of the prostate is a well established technique. Patients in this group are often at high risk for perioperative complications from concurrent diseases. The purpose of this study was to compare the elderly patients who received intrathecal fentanyl alone or intrathecal fentanyl plus bupivacaine or epidural anesthesia for tran...

conclusions dexmedetomidine added to bupivacaine in spinal anesthesia is more effective to increase duration of block, providing more appropriate sedation and less postoperative pain scale and post-operative nausea and vomiting (ponv) compared to fentanyl additive. results totally, 84 patients were randomly divided into three groups of 28 patients. onset of sensory block in dex group was signif...

The ultrastructural differentiation and central projection of identified bristle mechanosensory neurons were examined in Drosophila mutants lacking action potentials. Two mutations, parats1 and napts, are known to block axonal conduction in centrally located neurons at high temperatures. Their effects on epithelial sensory cells, which are derived from imaginal disks during pupation, have not b...

BACKGROUND Preliminary work has shown that ropivacaine provides spinal anaesthesia of shorter duration than bupivacaine, and may be of particular use in the day-case setting. However, there are few data comparing the actions of plain and hyperbaric solutions of this drug. METHODS Forty ASA grade I-II patients undergoing elective perineal surgery under spinal anaesthesia were randomized to rec...

PURPOSE We aimed to determine whether head elevation during combined spinal-epidural anesthesia (CSE) and Caesarean section provided improved hemodynamics and appropriate sensory block height. MATERIALS AND METHODS Forty-four parous women undergoing CSE for elective Caesarean section were randomly assigned to one of two groups: right lateral (group L) or right lateral and head elevated (group...

The adductor canal block (ACB) is newer compartment block of the saphenous nerve, which is a branch of femoral nerve, performed at the level of lower third of the thigh so that much of the motor innervation of the quadriceps group is spared, thus preserving much of the quadriceps strength making early ambulation and rehabilitation safer. The most significant advantage of the ACB over femoral ne...