Myiasis is a term derived from the Greek word "myia", meaning invasion of vital tissue of humans or other mammals by fly larvae. The deposited eggs develop into larvae, which penetrate deep structures causing adjacent tissue destruction. It is an uncommon clinical condition, being more frequent in underdeveloped countries and hot climate regions, and is associated with poor hygiene, suppurative...

Background: Ageing is associated with the diminished function of various tissues in the body. The gonadal function decreases with the increase in age. Testes undergo atrophy resulting in shrinkage of seminiferous tubules due to reduced testosterone hormone level in elderly male. The process of spermatogenesis decreases in old age when compared to young adults. Today’s lifestyle makes an adult s...

A fluid–structure interaction (FSI) numerical model of the aortic valve was used to simulate and compare young physiological aged operating conditions. The effect normal ageing considered by introducing alterations typically associated with senility: namely mild stiffening tissues progressive dilation chamber. aim this study is provide a haemodynamic baseline which allows assess typical variati...

This review summarizes the role of melatonin (MLT) in defense against toxic-free radicals and its novel effects in the development of the nervous system, and the effect of endogenously produced and exogenously administered MLT in reducing the degree of tissue and nerve injuries. MLT was recently reported to be an effective free radical scavenger and antioxidant. Since endogenous MLT levels fall...

Mortality differentials among urban residents who were classified by period of residence in a rapidly industrialized city were analysed for those aged 20 and over dying between April 1974 and March 1978. The highest mortality in the male population appeared in the group with under 5 years of residence, and this was attributed to the high age-specific death rates at age 50 and over. In females, ...

In a post-mortem analysis of 1,500 patients, aged 70 years or more, heart disease and malignancy were the two major causes of death. Coronary disease was exceedingly prevalent, almost one in five being subject to this form of heart disease, and 13% dying from its effects. The levelling of the sex ratio in coronary disease in the aged was a striking feature. The clinical manifestations of corona...

Alzheimer's disease is the prevalent cause of premature senility, a progressive mental disorder due to degeneration in brain and deposition of amyloid β peptide (1-42, a misfolded protein) in the form of aggregation that prevails for a prolonged time and obstructs every aspect of life. One of the primary hallmarks of the neuropathological disease is the accretion of amyloid β peptide in the bra...

This article is a response to David Armstrong's recent, revisionist account of the epidemiological transition which he claims replaced earlier discourses of ageing with new discourses of chronic disease. We argue (i) that he misrepresents a key element in Omran's account of the epidemiological transition, namely the decline in infant, child and maternal mortality; (ii) that he fails to acknowle...

Oral myiasis is a rare pathology and is associated with poor oral hygiene, alcoholism, senility, suppurating lesions, and severe halitosis. It arises from invasion of body tissues or cavities of living animals by maggots or larvae of certain dipterian flies. It is mostly reported in developing countries and in the tropics. We hereby report a rare case of oral myiasis in a 70-year-old female wit...