introduction: renin angiotensin system has an important role in blood pressure and renal functions. active angiotensin-converting enzyme 2 converts angiotensin i into angiotensin-(1-7) which is a vasodilator hormone and interacts with nitric oxide changes as well as other angiotensin ii receptors. in this study we evaluated the role of mas receptor antagonist (a779) and renal perfusion pressure...

• Interest in particular biologically active substances waxes and wanes. Investigators rush into a newly opened field, solve a few problems, and frequently raise more; then they rush out to follow more promising developments elsewhere. However, interest in angiotensins generally has persisted and increased. Observation of the actions of angiotensins has led to the study of enzymes involved in t...

The purpose of this brief review is to separate the characteristic properties and side effects attributable to the pharmacology of the whole class of angiotensin converting enzyme (ACE) inhibitors from those attributable to the chemical structure and kinetics of each particular ACE inhibitor. The former would be predictable and probably similar for all agents and, therefore, would be expected t...

Angiotensin-Converting Enzyme Inhibitors (ACEI) are commonly used to prevent cardiac remodeling in patients with ST-Segment Elevation Myocardial Infarction (STEMI).

fied in the stalk region. J Biol Chem 2001;276:5525–32. 21. Okabe T, Fujisawa M, Yotsumoto H, Watanabe J, Takaku F, Lanzillo JJ, et al. Familial elevation of serum angiotensin-converting enzyme. Q J Med 1985; 55:55–61. 22. Luisetti M, Martinetti M, Cuccia M, Dugoujon M, De Rose V, Peona V, et al. Familial elevation of serum angiotensin-converting enzyme activity. Eur Resp J 1990;3:441–6. 23. Kr...

[Purpose] This study aimed to assess the exercise capacity and muscle strength in elderly people using drugs for angiotensin-II blockage. [Subjects and Methods] Four hundred and seven older adults were recruited for this study. Data about comorbidities and medication use were recorded and the individuals were divided into three groups: control group- elderly people with normal exercise capacity...