نتایج جستجو برای: sedds
تعداد نتایج: 93 فیلتر نتایج به سال:
conclusions this study demonstrated that physicochemical properties, in vitro release and rat intestine permeability were dependent upon the contents of s/c, water and oil percentage in formulations. background self-emulsifying drug delivery system is an isotropic mixture of natural or synthetic oils, non-ionic surfactants or, one or more hydrophilic solvent and co-solvents/surfactant and polym...
The number of options available to drug discovery scientists to enhance the solubility of poorly soluble compounds by conventional formulation approaches is limited. In most cases, drug formulation is oriented toward the creation of a supersaturated solution upon contact with aqueous environment, often combined with solubilizing agents and precipitation inhibitors. The most popular formulations...
Received; August 4, 2005, Accepted; November 5, 2005 *To whom correspondence should be addressed : Hiroshi ARAYA, Formulation Technology Research Department, Pharmaceutical Technology Division, Chugai pharmaceutical Co., Ltd., 5-1, Ukima 5-chome, Kita-ku, Tokyo, 115-8543 Japan. Tel. +81-3-3968-4383, Fax. +81-3-39684810, E-mail: [email protected] Drug Metab. Pharmacokinet. 21 (1): 45–5...
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