Congenital High Airways Obstruction Syndrome (CHAOS) is a rare condition associated with high fetal or neonatal mortality. Prenatal diagnosis in the second trimester is made by the typical ultrasound features of large echogenic lungs, a flattened or inverted diaphragm, and fetal ascites or hydrops. We present two cases diagnosed at our institution; one in the second trimester, and a first trime...

The objective of this study was to examine the association of prenatal multivitamin/mineral supplement use during the first and second trimesters of pregnancy by low income, urban women in the Camden Study (1985-1995, n = 1,430) and preterm delivery (< 37 completed weeks) and infant low birth weight (< 2,500 g). Prenatal supplement use was corroborated by assay of circulating micronutrients at ...

Background The current study was designed to compare the effectiveness and side effects of oral, vaginal, and sublingual misoprostol in termination of second-trimester pregnancy. Materials and Methods: In this clinical trial (2014 to 2015), 85 pregnant women in the second trimester of pregnancy were included in Imam Reza hospital, Kermanshah, Iran. They were randomly divided into three groups a...

Immunosuppressive effect of pregnant serum obtained in the second and third trimesters was demonstrated in the PHA-induced homologous lymphocyte stimulation system, where 3H-thymidine incorporation into DNA was measured. Such an inhibitory factor was not present in the first trimester serum. The immunosuppressive principle detected in the second trimester serum was characterized by a potent inh...

background: various studies have come to contradictory results regarding the relationship between maternal hemoglobin (hb) level and adverse pregnancy outcomes. the present study aimed to investigate the birth outcomes among pregnant women who had normal hemoglobin levels in the first trimester of their pregnancy. patients and methods: in this prospective study, 108 healthy pregnant women with ...

OBJECTIVE To review the benefits of and requirements for a complete second trimester ultrasound and the documentation needed. OUTCOMES A complete second trimester ultrasound provides information about the number of fetuses, the gestational age, the location of the placenta, and fetal and maternal anatomy. EVIDENCE In the production of this document, the American Institute of Ultrasound in M...

BACKGROUND Maternal immunization against pertussis is currently recommended after the 26th gestational week (GW). Data on the optimal timing of maternal immunization are inconsistent. METHODS We conducted a prospective observational noninferiority study comparing the influence of second-trimester (GW 13-25) vs third-trimester (≥GW 26) tetanus-diphtheria-acellular pertussis (Tdap) immunization...

OBJECTIVE To ascertain, by means of a questionnaire, women's preferences for four different approaches to prenatal screening for Down syndrome. METHODS Women attending antenatal clinics at six UK maternity units were asked to put in order of preference four different approaches to screening for Down syndrome all of which had the same false positive rate of 5%. The options were: (1) first-trim...

Placenta accreta is a severe complication of pregnancy normally diagnosed during the second trimester. Early detection could reduce risk hemorrhage abortion or miscarriage; however, guidelines on first-trimester diagnosis are lacking. We describe case placenta first trimester with its sonographic and histological features.

BACKGROUND A major disadvantage of second trimester amniocentesis is that the result is usually available only after 18 weeks' gestation. Chorionic villus sampling (CVS) and early amniocentesis can be done between 9 and 14 weeks and offer an earlier alternative. OBJECTIVES The objective was to assess comparative safety and accuracy of second trimester amniocentesis, early amniocentesis, trans...