the pharmacokinetics of recombinant human erythropoietin (rhuepo) administered intravenously has been investigated in a group of five patients with chronic renal failure who were dialysis-dependent. the half-life of circulating erythropoietin decreased from 7.9±oa hr (mean ±so) at the beginning of treatment to 6.2±o.6 hr after 6 weeks and 5a±o.9 hr after 4 months of treatment. in spite of the s...

an experiment was conducted to investigate the effect of thyroid gland activity modulation (hyper or hypothyroidism) on energy utilization in broiler chickens. two hundred and forty one-day-old cobb broiler chicks were distributed into three dietary metabolizable energy (me) treatment groups (80 chicks each). the control group (e0) was fed basal diet (3150 kcal/kg diet), the second group (e1) w...

this experiment was conducted to evaluate the effects of different levels of dried aerial parts powder and extract of tanacetum balasmita (tb) medicinal plant on performance, carcass traits and blood parameters of broilers. two hundred eighty ross-308 broilers from 10 to 42 days of age were used in a completely randomized design in 5 treatments and 4 replicates (14 birds per replicate). the tre...

the imbalance between pro-oxidants and anti-oxidants leads to generation of oxygen/nitrogen free radicals which are implicated in several neurodegenerative diseases. fagonia arabica is an ethno-pharmacologically important ayurvedic herb known to have many medicinal properties like anti-inflammatory, analgesic and antipyretic effects. however, its antioxidant potential has not been investigated ...

N6-methyladenosine (m6A) methylation is a type of modification discovered on RNA molecules, mainly mRNAs, as well other RNAs. Similar to DNA methylation, m6A regulates the post-transcriptional expression level genes without altering their base sequences. It modulates gene by affecting binding mRNAs reader proteins, thereby regulating variable splicing, translation efficiency, and stability mRNA...

The peculiarities of the swimmers’ respiratory system response to a special physical load were studied. swimmers high sports qualification aged 16–18 years old, who specialize in swimming at distances various lengths, underwent examination. At first stage, we used exercises aimed enhancing anaerobic work power swimming. second parameters aerobic and zone third stage study, changes functions und...

Next to smoking, obesity is the second leading preventable risk factor for cancer, but increasing rates of and overweight are estimated overtake smoking as cancer factor. Few research studies have investigated dysregulated endocrine metabolism dietary phosphate a potential mediating in association with cancer. Phosphate toxicity, accumulation excess body from metabolism, associated tumorigenesi...

introduction: suspension of isolated hepatocyes is now being used in an increasing number of biochemical investigations, including drug metabolism and toxicity studies. isolated hepatocyes, retain many of the essential properties of the intact tissue including permeability charactreristics. material and methods: in this method at first liver is subjected to a nonrecirculating perfusion with cal...