The sebum excretion rate has been found to be increased in female patients with phenylketonuria. This may be related to a depletion of midbrain dopamine and release of the sebotrophic hormone.

as one of the major constituents, accounting for about 16% of the unsaponifiable matter and about 35% of the hydrocarbon fraction. Some preliminary chemical tests were made for the fatsoluble vitamins, and the presence ofa small amount of vitamin E in human sebum was reported. A more complete study of the unsaponifiable matter has now been made, and this material has been more thoroughly examin...

The delay between synthesis and excretion of sebum in sheep and in man was determined by measurement of the time between intradermal injection of (1"C ]acetate and the appearance of a peak of radioactivity in the skin surface lipids at the injection site. In two sheep, a peak of radioactivity in the total surface lipid occurred 6 days after injection, and this is interpreted as the time require...

A NMR spectroscopic method is described that enables the quantitation of specific lipid classes and components, independent of fatty acid composition. We demonstrate this method for measuring cholesterol, squalene, and pools of sterol esters, wax esters (WEs), and triglyceride (TG) components in sebum and meibum. When 600 MHz NMR equipment is used in conjunction with highly sensitive cryogenica...

The sebum has important protective functions for the skin, although its overproduction may lead to undesired aesthetic problems and even more serious skin diseases. Sebum overproduction is caused by the androgen hormone testosterone, which is regulated by the enzyme 5-α Reductase, and can be associated with an over-proliferation of parasitic microbes that cause serious infections linked to skin...

Objective. Bokusoku (BK) is an extract from the Quercus cortex used in folk medicine for treatment of skin disorders and convergence, and is present in jumihaidokuto, a traditional Japanese medicine that is prescribed for purulent skin diseases like acne vulgaris. The excess of sebum production induced by androgen is involved in the development of acne. Our aim is to examine whether BK and its ...

The present study was planned to test the efficacy of Moringa oleifera on undesirable skin sebum secreted by sebaceous glands during winter season in humans. For this purpose, an extract of Moringa leaves was prepared due to strong antioxidant activity. 3% Moringa leaves extract was incorporated in active cream and the base was without extract. The study was conducted during the winter season (...

We present highly sensitive, reliable methods for the determination of platinum originating from carboplatin in canine sebum and cerumen. The methods are based on the measurement of platinum by inductively coupled plasma mass spectrometry and allow quantification of 0.15 pg platinum per cm² body surface in canine sebum and of 7.50 pg platinum per sampled ear canal. The sample pretreatment proce...

this merely emphasizes the importance of the question as to the role of the several dietary elements in this effect. The first item for consideration, obviously, is the cholesterol in the diet. We have already reported briefly both survey and experimental evidence indicating that the cholesterol in ordi nary human diets has substantially no effect on the concen tration in the blood (Keys, '49, ...