Human umbilical vein endothelial cells (HUVECs) were used to gain insight into the molecular mechanism whereby the major extracellular protease from group A streptococci damages host tissue. HUVECs exposed to streptococcal cysteine protease (SCP) for various times exhibited cytopathic effect and cell detachment from the culture vessel. Gelatin substrate zymography showed that a time- and concen...

Beyond the optimization of single parameter (usually the wire-length) in Standard Cell Placement (SCP), focus in the present work is laid on the optimization of speed, power, and the wire length. As discussed in our previous work of hybrid algorithms for single objective optimization of SCP the main advantage of hybridization is the improvement in convergence speed to Pareto front although it l...

Although reverse cholesterol transport from peripheral cell types is mediated through plasma membrane microdomains termed lipid rafts, almost nothing is known regarding the existence, protein/lipid composition, or structure of these putative domains in liver hepatocytes, cells responsible for the net removal of cholesterol from the body. Lipid rafts purified from hepatocyte plasma membranes by ...

It was confirmed that delta 5,7-sterol delta 7-reductase activity was suppressed by cholecalciferol (vitamin D3) in the enzyme system consisted of microsomes and sterol carrier protein (SCP). The enzyme activity was significantly decreased in the combination with microsomes obtained from either vitamin D-deficient or vitamin D3-treated rat liver and with SCP obtained from vitamin D3-treated rat...

Introduction. Operant conditioning of one’s slow cortical potential (SCP) or sensorimotor rhythm (SMR) can be used to control epilepsy or to manipulate external devices, as applied in BCI (Brain-Computer Interface). A commonly accepted view that both SCP and SMR are reflections of central arousal suggests a functional relationship between SCP and SMR networks. Method. The operant conditioning o...

the present study surveys the effect of bank-specific, industry-specific and macroeconomic conditions on bank performance to examine the structure-conduct-performance (scp) hypothesis in iranian banking industry. to achieve this goal, we drew upon the panel data technique to analyze the data of eleven public and private iranian banks during 2001-2006. firstly, productivity was calculated by usi...

The design and development of artificial metal-free photoenzymes aims to combine the selectivity enzymatic reactions with benefits modern synthetic photocatalysts. Removing need for rare earth metals allowing milder reaction conditions, leading a more sustainable catalytic system. Here, we present novel photoenzyme by integrating an organophotocatalytic moiety based on donor-acceptor into stero...

Successful single-cell isolation is a primary step for subsequent chemical and biological analyses of single cells. Conventional single-cell isolation methods often encounter operational complexity, limited efficiency, deterioration of cell viability, incompetence in the isolation of a single-cell into nanoliter liquid, and/or inability to select single adherent cells with specific phenotypes. ...

This study assessed whether combining adipose-derived mesenchymal stem cells (ADMSC) with preactivated, disaggregated shape-changed platelets (PreD-SCP) was superior to either therapy alone for protecting rat lung from acute respiratory distress syndrome (ARDS) complicated by sepsis. ARDS and sepsis were induced through 100% oxygen inhalation and peritoneal administration of 1.5 mg/kg lipopolys...

Equilibrium binding studies show that 6 atoms of calcium are bound by the dimeric molecule of the sarcoplasmic calcium-binding protein (SCP) from crayfish. SCP exhibits positive cooperativity in calcium-binding for four sites, as indicated by increasing intrinsic binding constants (1 to 5 x 10” M-l), and negative cooperativity for the other two sites (decreasing constants from 5 to 0.8 x lo7 M-...