Sir William Read, Royal Ophthalmologist during the reign of Queen Anne (1702-17I4), who incidentally was unable to read or write (Guthrie, 1958), gave a choice description of the dangers of perforation in deep scleritis: 'For it is most certain that this horny membrane . . . by how much deeper the blister is hidden in the membrane . . . in danger to make an ulceration by breaking through the me...

INTRODUCTION Scleritis and peripheral ulcerative keratitis are ocular manifestations found in many inflammations and infections. Therefore, their association should prompt a search for inflammatory or infectious causes that may be life-threatening, especially in the context of AIDS due to HIV infection. FINDINGS We report the case of a 37-year-old female, first seen in 2011 with a nodular scl...

RATIONALE Surgically induced scleritis is a rare complication following ophthalmologic surgery such as cataract surgery, pterygium excision, strabismus surgery, and retinal detachment repair. Rheumatoid arthritis (RA) is the connective tissue disease most commonly associated with scleritis. PATIENT CONCERNS A 70-year-old woman visited our clinic with complaint of visual disturbance, ocular pa...

Sir William Read, Royal Ophthalmologist during the reign of Queen Anne (1702-17I4), who incidentally was unable to read or write (Guthrie, 1958), gave a choice description of the dangers of perforation in deep scleritis: 'For it is most certain that this horny membrane . . . by how much deeper the blister is hidden in the membrane . . . in danger to make an ulceration by breaking through the me...

PURPOSE To determine the clinical value of serological testing in patients with idiopathic scleritis. DESIGN Retrospective case series. METHODS Medical records of patients with scleritis seen at an institutional referral center over an 11-year period were reviewed. RESULTS Of 119 patients with scleritis seen at the University of Illinois Uveitis Clinic, 91 (76.5%) patients had no known et...

BACKGROUND The purpose of this study is to report the management of non-necrotizing anterior scleritis with a single-dose subconjunctival 0.7 mg dexamethasone implant (Ozurdex®, Allergan, Inc., CA, USA). Six patients with clinical diagnosis of non-necrotizing anterior scleritis (diffuse, sectorial, and nodular) were submitted to subconjunctival injection of dexamethasone implant. The injection ...

INTRODUCTION To evaluate the complications, efficacy of medical and surgical treatment, and outcome in patients with necrotizing scleritis and peripheral ulcerative keratitis associated with Wegener's granulomatosis. METHODS The authors reviewed a series of seven patients with Wegener's granulomatosis treated in the Corneal Department of Zhongshan Ophthalmic Center and the Department of Ophth...

PURPOSE The aim of this case report was to describe a patient who presented with Pseudomonas scleritis after pterygium excision. The study was conducted at the Department of Ophthalmology, Faculty of Medicine, Chiang Mai University in Chiang Mai, Thailand. METHODS The record of a patient who was diagnosed as Pseudomonas scleritis after pterygium excision was retrospectively reviewed for histo...

Infectious necrotizing scleritis is a rare but devastating disease that often develops after trauma or surgery. A delay in the diagnosis or inappropriate treatment can cause a progression of the infection to scleral thinning and even perforation of the eye, resulting in endophthalmitis and blindness. For cases that do not respond to medical therapy or when the necrosis has advanced to perforati...

A 41-year-old asymptomatic woman was referred for enucleation of a 7. 5-mm-thick intraocular tumor suspected to be choroidal melanoma. The clinical findings combined with imaging studies suggested instead a diagnosis of giant nodular posterior scleritis. A scleral biopsy was performed to confirm the diagnosis. After 12 years of observation, the lesion has remained stable and visual acuity has b...