Melatonin has been suggested as a new natural pain killer in inflammatory pain and during surgical procedures. We designed this randomized double-blind controlled study to evaluate the analgesic efficacy and also optimal preemptive dose of melatonin in patients undergoing cesarean section under spinal anesthesia.One hundred twenty patients scheduled for cesarean section under spinal anesthesia ...

Abstract Background This prospective randomized study was performed on 80 patients, 21–60 years old, scheduled for open nephrectomy surgery. Patients were equally allocated to two groups: the transversus abdominis plane block (TAPB) group and quadratus lumborum (QLB) group. Both groups received 0.3 ml/kg of bupivacaine 0.25% side operation. Total postoperative pethidine consumption, time rescue...

To analyze the analgesic effect of flurbiprofen axetil in combination with fentanyl on patients after laparoscopic cholecystectomy is objective study. Between April 2020 and 2021, a total 120 who received delayed or scheduled were enrolled into this study divided control group observation according to their admission sequence, 60 each group. Patients for postoperative analgesia, while those fen...

Introduction: Adjuvants are used in conjunction with local anaesthetics for brachial plexus block to quicken onset, prolong duration and augment the quality of anaesthesia.
 Objectives: The study aims evaluate effect adding ultra-low dose naloxone bupivacaine on postoperative analgesia.
 Methodology: A prospective, randomized, double-blind was conducted including forty American Societ...

it has been sugeested since long that peripheral nerves possess opiod receptors and this has tempted clinicans in adding narcotics to local anesthetics to prolong the analgesic effects of these solutions. in this regard, we studied 45 patients undergoing surgical procedures on upper extremities. the patients scheduled for surgery were divided in to three groups, each comprising of 15 patients a...

BACKGROUND The purpose of this study was to compare electrophysiologically guided and traditional nerve stimulator analgesia femoral nerve block after total knee arthroplasty. METHODS Patients scheduled for unilateral total knee arthroplasty were randomized to electrophysiologically guided or traditional nerve stimulator analgesia by pre-emptive single injection femoral nerve block with corre...

CONTEXT Hormonal and mechanical factors make obstetric patients need strict dose calculations of local anesthetics intrathecally for spinal anesthesia. Any greater dose of local anesthetics can cause hemodynamic instability, maternal morbidity and any lesser dose can produce inadequate block. Hence, we hypothesized in our study that by using low dose of bupivacaine with fentanyl can maintain st...

1. Chin RP, Ho CH, Cheung LP. Scheduled analgesic regimen improves rehabilitation after hip fracture surgery. Clin Orthop Relat Res 2013;471:2349‐60. 2. Salgado PF, Sabbag AT, Silva PC, Brienze SL, Dalto HP, Módolo NS, et al. Synergistic effect between dexmedetomidine and 0.75% ropivacaine in epidural anesthesia. Rev Assoc Med Bras 2008;54:110‐5. 3. Saadawy I, Boker A, Elshahawy MA, Almazrooa A...

Background: Pectoralis-Serratus interfascial plane block is a peripheral of the thoracic wall that presents analgesia its anterolateral portion. Dexmedetomidine, specific α-2 adrenoceptor agonist, has sedative, anxiolytic, and analgesic properties. The aim this work was to assess safety efficacy in contrast with dexmedetomidine infusion for unilateral radical mastectomy.
 Methods: This pro...

Background: Transversus Abdominis Plane (TAP) block is a regional anaesthetic technique used for postoperative pain management following abdominal surgery. Local anesthetics like bupivacaine can be in this and it performed various approaches. Among them ultrasound-guided lateral posterior approaches are popular. Objective: Aim of study to compare the effectiveness TAP using post-operative after...