OBJECTIVE To estimate the burden of cardiovascular disease within 15 European Union countries (before the 2004 enlargement) as a result of excess dietary saturated fats attributable to the Common Agricultural Policy (CAP). METHODS A spreadsheet model was developed to synthesize data on population, diet, cholesterol levels and mortality rates. A conservative estimate of a reduction in saturate...

Coagulation and platelet aggregation induced by thrombin, ADP, adrenaline, and collagen were studied in three contrasted groups, each of 20 to 22 middle-aged male farmers. Serum lipids were similar in the three groups. In the west of Scotland group, however, platelet reactivity was significantly greater than in the east of Scotland. This was associated with a dietary intake, evaluated by three ...

OBJECTIVE Low-density lipoprotein receptor-related protein 1 (LRP1) is a multifunctional endocytic receptor that is highly expressed in adipocytes and the hypothalamus. Animal models and in vitro studies support a role for LRP1 in adipocyte metabolism and leptin signaling, but genetic polymorphisms have not been evaluated for obesity in people. DESIGN AND METHODS We examined whether dietary f...

BACKGROUND [corrected] In order to ascertain the food intake and nutritional situation of the children of the Community of Madrid, on which no updated information was available, the Institute of Public Health conducted the 2001/2001 Children's Nutrition Survey of the Community of Madrid (CNSCM). This study offers an analysis of the CNSCM that describes and evaluates the food, energy and nutrien...

INTRODUCTION High dietary saturated fat intake is associated with higher blood concentrations of low-density lipoprotein cholesterol (LDL-C), an established risk factor for coronary heart disease. However, there is increasing interest in whether various dietary oils or fats with different fatty acid profiles such as extra virgin coconut oil may have different metabolic effects but trials have r...

Background Research suggests that not all fats are created equal, particularly when it comes to heart health. In fact, various dietary fats or fatty acids can have different effects on blood lipids associated with coronary heart disease (CHD) such as HDL (“good”) cholesterol, LDL (“bad”) cholesterol, and triglycerides. Trans fatty acids and high amounts of certain saturated fatty acids (SFA) in...

Dietary fats have important effects on the risk of cardiovascular disease (CVD). Abundant evidence shows that partial replacement of saturated fatty acids (SAFA) with unsaturated fatty acids improves the blood lipid and lipoprotein profile and reduces the risk of coronary heart disease (CHD). Low-fat diets high in refined carbohydrates and sugar are not effective. Very long-chain polyunsaturate...

Mol. Nutr. Food Res. 2020, 65, 1901071 DOI: 10.1002/mnfr.201901071 Dietary stressors, including saturated fats and sugars, generate endogenous stress signals that reconfigure host metabolism towards a glycolytic pro-inflammatory state. Conversely, exercise, unsaturated fats, dietary antioxidants direct oxidative phosphorylation lower reactive oxygen species. This metabolic environment promotes ...

BACKGROUND A role of energy and various nutrients, including protein, sugar, saturated and unsaturated fats, in colorectal cancer risk has been suggested, but should be better defined. PATIENTS AND METHODS The association between dietary intake of various macronutrients and colorectal cancer risk was analysed using data from a case-control study conducted between 1992 and 2000 in the Swiss Ca...

The effects of dietary unsaturated and saturated fats on chemically induced colon carcinogenesis were examined in male Donryu rats. The rats were fed two types of semipurified diets consisting of 5% linoleic acid or 4.7% stearic acid plus 0.3% essential fatty acid as dietary fats. The rats were treated with azoxymethane (7.4 mg/kg body weight) s.c. once a week for 11 weeks and sacrificed 15 wee...